368422-27-9 Usage
Uses
Used in Pharmaceutical Industry:
2-(methoxymethoxy)-5-(trifluoromethyl)benzoic acid is used as an intermediate in the synthesis of various drugs and active pharmaceutical ingredients. Its unique chemical structure allows for the development of new and innovative medications with improved efficacy and safety profiles.
Used in Material Development:
2-(methoxymethoxy)-5-(trifluoromethyl)benzoic acid is used as a key component in the development of various materials, leveraging its unique chemical properties to create novel materials with enhanced performance characteristics.
Used in Agrochemical Products:
2-(methoxymethoxy)-5-(trifluoromethyl)benzoic acid is utilized in the formulation of agrochemical products, where its unique chemical properties contribute to the development of more effective and targeted pest control solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 368422-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,8,4,2 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 368422-27:
(8*3)+(7*6)+(6*8)+(5*4)+(4*2)+(3*2)+(2*2)+(1*7)=159
159 % 10 = 9
So 368422-27-9 is a valid CAS Registry Number.
368422-27-9Relevant academic research and scientific papers
Fluorophenols and (trifluoromethyl)phenols as substrates of site-selective metalation reactions: To protect or not to protect
Marzi, Elena,Mongin, Florence,Spitaleri, Andrea,Schlosser, Manfred
, p. 2911 - 2915 (2007/10/03)
O-Methoxymethyl (MOM) protected fluorophenols can be cleanly metalated and subsequently be submitted to site-selective electrophilic substitution. The 2- and 4-isomers exhibit ambivalent reactivity: deprotonation occurs at the position adjacent to the oxygen when butyllithium is employed whereas the position adjacent to the fluorine is attacked by the superbasic mixture of butyllithium and potassium tert-butoxide (LIC-KOR). The MOM-protected (trifluoromethyl)-phenols react exclusively at oxygen-neighboring positions. The meta isomer provides another example of optional site selectivity, undergoing hydrogen/metal exchange at the 2-position with the LIC-KOR reagent and at the 6-position with sec-butyllithium. Unprotected (trifluoromethyl)phenols can also be ortho-metalated after O-deprotonation, although the products are formed in only moderate yields.
