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N-Boc-3-amino-2-formylthiophene is a chemical compound that features a 3-amino-2-formylthiophene core with an N-tert-butoxycarbonyl (N-Boc) protecting group. N-Boc-3-amino-2-formylthiophene is characterized by its five-membered thiophene ring, which includes a sulfur atom, and functional groups such as the formyl group with a carbonyl bonded to a hydrogen atom and the amino group with a nitrogen atom bonded to two hydrogen atoms. The N-Boc group serves to protect the amino group, allowing for controlled reactivity in chemical reactions.

368442-47-1

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368442-47-1 Usage

Uses

Used in Organic Synthesis:
N-Boc-3-amino-2-formylthiophene is utilized as a building block in organic synthesis for the creation of a variety of compounds. Its unique structure and reactivity make it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-Boc-3-amino-2-formylthiophene is employed as a key intermediate for the development of pharmaceutical products. Its presence in the molecular structure can contribute to the biological activity of the final drug, making it an essential component in drug discovery and design.
Used in Agrochemical Products:
N-Boc-3-amino-2-formylthiophene also finds application in the agrochemical industry, where it serves as a precursor for the synthesis of various agrochemicals. Its role in these products is crucial for the development of effective and targeted agrochemicals for agricultural use.
The N-Boc protecting group plays a significant role in these applications by ensuring that the amino group's reactivity is controlled during the synthesis process, which is vital for achieving the desired outcomes in the final products.

Check Digit Verification of cas no

The CAS Registry Mumber 368442-47-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,8,4,4 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 368442-47:
(8*3)+(7*6)+(6*8)+(5*4)+(4*4)+(3*2)+(2*4)+(1*7)=171
171 % 10 = 1
So 368442-47-1 is a valid CAS Registry Number.

368442-47-1 Well-known Company Product Price

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  • Aldrich

  • (762210)  N-Boc-3-aminothiophene-2-carboxaldehyde  97%

  • 368442-47-1

  • 762210-500MG

  • 947.70CNY

  • Detail

368442-47-1Relevant academic research and scientific papers

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

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Page/Page column 66, (2008/06/13)

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins

Fang, Yuan-Qing,Yuen, Josephine,Lautens, Mark

, p. 5152 - 5160 (2008/02/07)

(Chemical Equation Presented) A palladium-catalyzed reaction of gem-dichloroolefins and a boronic acid via a tandem intramolecular C-N and intermolecular Suzuki coupling process gave corresponding substituted azaindoles or thienopyrroles. This method is a

NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND

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Page/Page column 74, (2010/11/08)

The present invention provides an antifungal agent represented by the formula: [wherein A1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X1 represents a group represented by the formula -NH-C(=O)-, a group represented by the formula -C(=O)-NH-, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A1 may have 1 to 3 substituents, and E has one or two substituents].

Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studies

Whittamore, Paul R.O.,Addie, Matthew S.,Bennett, Stuart N.L.,Birch, Alan M.,Butters, Michael,Godfrey, Linda,Kenny, Peter W.,Morley, Andrew D.,Murray, Paul M.,Oikonomakos, Nikos G.,Otterbein, Ludovic R.,Pannifer, Andrew D.,Parker, Jeremy S.,Readman, Kristy,Siedlecki, Pawel S.,Schofield, Paul,Stocker, Andy,Taylor, Melvyn J.,Townsend, Linda A.,Whalley, David P.,Whitehouse, Jennifer

, p. 5567 - 5571 (2007/10/03)

Two series of novel thienopyrrole inhibitors of recombinant human liver glycogen phosphorylase a (GPa) which are effective in reducing glucose output from rat hepatocytes are described. Representative compounds have been shown to bind at the dimer interface site of the rabbit muscle enzyme by X-ray crystallography.

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