3685-84-5 Usage
Pharmacological action
Meclofenoxate hydrochloride(MecloCl) [CAS,NO:51-68-3], an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
Meclofenoxate hydrochloride is a psychostimulant in the nootropic agent group available in capsule and tablet formulations approved for traumatic cataphora, alcoholic poisoning, anoxia neonatorum, and children's enuresis in China. Although these 2 generic formulations are marketed in China, information regarding their pharmacokinetics and bioequivalence in humans has not been published. Meclofenoxate hydrochloride appears to increase the consolidation of new information into long-term memory. Meclofenoxate does not affect other aspects of remembering. Meclofenoxate is found that significantly more of the subjects receiving meclofenoxate reportes an increased level of mental alertness.
Uses
Different sources of media describe the Uses of 3685-84-5 differently. You can refer to the following data:
1. The applications of is Meclofenoxate hydrochloride:
Memory decline through aging
Dementia and Alzheimer’s (clinically)
?Brain damage or injuries
Alcohol or drug abuse symptoms and effects
Promote the metabolism of brain
2. Meclofenoxate is a cerebral stimulant. Also, Meclofenoxate is used as plant growth regulator.
3. Plant growth regulator.
4. Cerebral stimulant;Acetylcholine precursor
Chemical Properties
White Solid
Safety Profile
Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.When heated to decomposition it emits very toxic fumes ofCl??, NOx, and HCl.
Check Digit Verification of cas no
The CAS Registry Mumber 3685-84-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3685-84:
(6*3)+(5*6)+(4*8)+(3*5)+(2*8)+(1*4)=115
115 % 10 = 5
So 3685-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
3685-84-5Relevant articles and documents
A meclofenoxate hydrochloride preparation method
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Paragraph 0035-0040; 0041; 0044, (2019/03/25)
The invention discloses a meclofenoxate hydrochloride of the preparation method, comprises the following steps: (A) will acid with thionyl chloride in chlorobenzene acyl chloride reaction, to obtain the chlorophenoxy acetyl chloride; (B) step (A) to get chlorophenoxy acetyl chloride and dimethyl amino ethanol by condensation reaction to obtain the meclofenoxate free alkali; (C) step (B) to obtain the free base of the salt-forming acid salt, thermal insulation and filtering to obtain the hydrochloride. The invention easy availability of raw materials, the reaction temperature is low, the operation is convenient, the crude product of high purity, stable quality, the present invention provides a more easy operation, more environmentally friendly, more economic meclofenoxate hydrochloride synthetic pathway.
Preparation and preliminary pharmacological study of the dimethylamino-ethyl esters of various acids acting as plant growth regulators.
THUILLIER,RUMPF,THUILLIER
, p. 2081 - 2083 (2007/11/05)
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