36852-58-1Relevant academic research and scientific papers
Exploration of the chemical space of novel naphthalene-sulfonamide and anthranilic acid-based inhibitors of penicillin-binding proteins
Sosic, Izidor,Turk, Samo,Sinreih, Masa,Trost, Nusa,Verlaine, Olivier,Amoroso, Ana,Zervosen, Astrid,Luxen, Andre,Joris, Bernard,Gobec, Stanislav
scheme or table, p. 380 - 388 (2012/09/05)
Penicillin-binding proteins are a well established, validated and still a very promising target for the design and development of new antibacterial agents. Based on our previous discovery of several noncovalent small-molecule inhibitor hits for resistant
Oxazinoquinolones useful for the treatment of viral infections
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Page column 8, (2010/11/29)
The present invention provides a compound of formula I These compounds are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
Synthesis of 5-(tert-Butoxycarbonylaminoacetoxymethyl)-2-nitrophenoxyacetic Acid
Selivanov,Kulikov,Ginak
, p. 394 - 400 (2007/10/03)
5-(tert-Butoxycarbonylaminoacetoxymethyl)-2-nitrophenoxyacetic acid was synthesized in seven steps starting from 5-methyl-2-nitrophenol. Its phenyl ester was selectively hydrolyzed with triethylamine in aqueous dioxane. 5-Hydroxymethyl-2-nitrophenoxyacetic acid was formed as by-product. Its formation was proved by independent synthesis from 1-acetoxy-5-bromomethyl-2-nitrobenzene. Experimental difficulties that arise along other routes to the target compound are discussed.
