3687-64-7Relevant academic research and scientific papers
Creation of an α-mannosynthase from a broad glycosidase scaffold
Yamamoto, Keisuke,Davis, Benjamin G.
supporting information; experimental part, p. 7449 - 7453 (2012/09/21)
α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated conjugates using the α-mannosynthase displaying low (unwanted) oligomerization activity. Copyright
Production of galactinol from sucrose by plant enzymes.
Wakiuchi, Nariaki,Shiomi, Ryohei,Tamaki, Hajime
, p. 1465 - 1471 (2007/10/03)
Galactinol, 1-O-(alpha-D-galactopyranosyl)-myo-inositol, was produced from sucrose as a starting material. UDP-Glc was prepared with sucrose and UDP using sucrose synthase partially purified from sweet potato roots. Then, the UDP-Glc was converted to UDP-Gal using yeast UDP-Gal 4-epimerase from a commercial source. Finally, galactinol was produced from the UDP-Gal and myo-inositol using galactinol synthase partially purified from cucumber leaves. The product was identified as galactinol by the retention times of HPLC, alpha-galactosidase digestion, and NMR spectrometry.
Syntheses of penta-O-benzyl-myo-inositols, O-β-L-arabinosyl-(1 → 2)sn-myo-inositol, O-α-D-galactosyl-(1 → 3)-sn-myo-inositol, and O-α-D-galactosyl-(1 → 6)-O-α-D-galactosyl-(1 → 3)-sn-myo-inositol
Koto,Hirooka,Yoshida,Takenaka,Nagamitsu,Sakurai,Zen,Yago,Tomonaga
, p. 2521 - 2529 (2007/10/03)
Two-step conversions of myo-inositol into (±)-2,3,4,5,6- and 1,3,4,5,6-penta-O-benzyl-myo-inositols are described. Starting from these monohydroxy derivatives of myo-inositol, O-β-L-arabinopyranosyl-(1→2)-sn-myo-inositol from Japanese green tea, Camellia sinensis, and O-α-D-galactopyranosyl-(1→3)-sn-myo-inositol (galactinol) as well as its homolog, O-α-D-galactopyranosyl-(1→6(II))-galactinol, were synthesized by way of the in situ activating glycosylation procedure.
DERIVATIVES OF ASYMMETRICALLY SUBSTITUTED MYO-INOSITOL. XXXIII. SYNTHESIS OF DIASTEROMERIC MANNOSIDES OF MYO-INOSITOL
Sibrikov, Yu. I.,Stepanov, A. E.,Shvets, V. I.
, p. 470 - 476 (2007/10/02)
Diastereomeric acetylated mannosides of myo-inositol were synthesized by the glycosylation of the racemic acetates of myo-inositol with the ethyl orthoacetate of D-mannose.The synthesized mannosides of myo-inositol can be used for the production of chiral myo-inositol acetates and as intermediates in the synthesis of complex phosphoinositides.
