368837-34-7

Basic information

• Product Name: 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine
• Synonyms: 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine
• CAS NO: 368837-34-7
• Molecular Weight: 251.344
• Mol File: 368837-34-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine(368837-34-7)
• EPA Substance Registry System: 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethanamine(368837-34-7)

Safety Data

• Hazardous Substances Data: 368837-34-7(Hazardous Substances Data)

Upstream product

• 1581258-45-8 (Z)-ethyl 2-cyano-2-(2,2-dimethyltetrahydropyran-4-ylidene)acetate 
• 120729-52-4 ethyl <2,2-dimethyl-4-(p-fluorophenyl)-4-tetrahydropyranyl>cyanacetate 
• 64792-49-0 Ethyl (2,2-dimethyl-4-tetrahydropyranylidene)cyanoacetate 
• 330998-24-8 2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)acetonitrile 
• 1194-16-7 2,2-dimethyltetrahydropyran-4-one 

Downstream Products

• 1581258-25-4 6-(2,5-difluorophenyl)-N-(2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethyl)pyrazin-2-amine 
• 1581258-50-5 6-chloro-N-(2-(4-(4-fluorophenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethyl)pyrazin-2-amine 
• 1313603-11-0 {2-[4-(4-fluorophenyl)-2,2-dimethyltetrahydropyran-4-yl]ethyl}-(3-methoxyphenyl)amine 

Relevant articles and documents

TETRAHYDROPYRAN-4-YLETHYLAMINO- OR TETRAHYDROPYRANYL-4-ETHYLOXY-PYRIMIDINES OR -PYRIDAZINES AS ISOPRENYLCYSTEINCARBOXYMETHYL TRANSFERASE INHIBITORS

A compound of formula (I): wherein: R1 is selected from: (i) phenyl, optionally substituted by one fluoro group; (ii) thienyl; (iii) furanyl; (iv) C1-4 alkyl; and (v) H; R2 is selected from: (II), R3 is selected from: (III), X is selected from NH and O; R4 is selected from phenyl, a 5-membered heteroaryl or a 6-membered heteroaryl, all of which are optionally substituted by one or more substituents selected from the group consisting of: methyl, methoxy, trifluoromethyl, trifluoromethoxy, cyano, fluoro, -OC2H4OMe, and pyrazolyl.