36916-95-7Relevant academic research and scientific papers
Rhodium(I)-Catalyzed Coupling-Cyclization of C=O Bonds with α-Diazoketones
Chen, Ziyang,Hu, Xinwei,Huang, Junmin,Zeng, Wei
, p. 3980 - 3983 (2018)
An unprecedented intermolecular nucleophilic attack of C=X bonds (X = O and S) on the rhodium(I)-carbenes has been developed. This transformation allows for the coupling-cyclization of aroylamides with α-diazoketones and provides concise access to 2,4,5-trisubstituted 1,3-oxazoles and 1,3-thiazoles with a broad tolerance of functional groups.
