370581-85-4

Upstream product

• 37746-78-4 4-bromo-trans-crotonic acid ethyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 119011-89-1 (Z)-ethyl 4-bromobut-2-enoate 
• 1303556-18-4 (E)-ethyl 4-(tert-butoxycarbonyloxy)but-2-enoate 
• 100-49-2 cyclohexylmethyl alcohol 

Downstream Products

• 370581-89-8 5-cyclohexyl-5-hydroxy-pent-2-enoic acid ethyl ester 

Relevant academic research and scientific papers

Development of a highly α-regioselective metal-mediated allylation reaction in aqueous media: New mechanistic proposal for the origin of α-homoallylic alcohols

This paper described a general method to obtain α-adduct homoallylic alcohols using indium, zinc, and tin in water. A new mechanism was proposed to account for the formation of these synthetically difficult-to-obtain molecules. Generally, this method can

Enantioselective iridium-catalyzed vinylogous reformatsky-aldol reaction from the alcohol oxidation level: Linear regioselectivity by way of carbon-bound enolates

Reformatsky reinvented: Highly enantioselective vinylogous Reformatsky-type addition has been achieved from the alcohol oxidation level with linear regioselectivity through carbon-bound enolates (see scheme; Boc=tert- butoxycarbonyl). Complete levels of c

Indium trichloride-promoted tin-mediated carbonyl allylation in water: High simple diastereo- and diastereofacial selectivity

Tin-mediated additions of allylic bromides to aldehydes and aldoses leads to adduct with high diastereo- and diastereofacial selectivity in the presence of indium trichloride in water.