370581-89-8

Upstream product

• 37746-78-4 4-bromo-trans-crotonic acid ethyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 370581-85-4 2-(cyclohexyl-hydroxy-methyl)-but-3-enoic acid ethyl ester 
• 221676-47-7 1-cyclohexyl-2-methyl-but-3-en-1-ol 

Relevant academic research and scientific papers

Development of a highly α-regioselective metal-mediated allylation reaction in aqueous media: New mechanistic proposal for the origin of α-homoallylic alcohols

This paper described a general method to obtain α-adduct homoallylic alcohols using indium, zinc, and tin in water. A new mechanism was proposed to account for the formation of these synthetically difficult-to-obtain molecules. Generally, this method can

The first In(OTf)3-catalyzed conversion of kinetically formed homoallylic alcohols into the thermodynamically preferred regioisomers: Application to the synthesis of 22α-sterols

A retro-ene reaction that generates the parent aldehyde and a sigmatropic rearrangement are involved in the In(OTf)3-catalyzed conversion of homoallylic alcohols 1 into the thermodynamically favored regioisomers 2. This method can be used for the stereocontrolled synthesis of linear homoallylic 22α-sterols from their readily accessible branched 22β isomers.