370595-47-4

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 370595-46-3 (+)-6-[2-(methoxycarbonyl)ethenyl]-2'-deoxyuridine 
• 370595-45-2 (+)-6-[2-(methoxycarbonyl)ethenyl]-2'-deoxyuridine-3',5'-(1,1,3,3-tetraisopropyl)disiloxane 
• 149857-04-5 1-[3,5-Bis-O-(1,1,3,3-tetraisopropyldisilox-1,3-diyl)-2-deoxy-β-D-erythro-furanosyl]uracil-6-carboxaldehyde 
• 98495-56-8 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine 
• 951-78-0 2'-deoxyuridine 

Downstream Products

• 370595-49-6 (2E)-3-[3-(5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxytetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]-N-[6-({[5-(dimethylamino)-1-naphthyl]sulfonyl}amino)hexyl]acrylamide 
• 370595-50-9 (2E)-3-[3-(5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxytetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]-N-[6-(9H-carbazol-2-yloxy)hexyl]acrylamide 
• 370595-48-5 (2E)-3-[3-(5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxytetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]-N-[6-({[3-(4-nitrophenyl)-1-adamantyl]acetyl}amino)hexyl]acrylamide 

Relevant academic research and scientific papers

Synthesis of hapten-phosphoramidites from 2′-deoxyuridine

A total of 11 novel phosphoramidites, 3a-d, 4a-d and 14a-c were prepared from 2′-deoxyuridine functionalized at 5 and 6-position of the pyrimidine ring with hapten reporter groups, e.g. adamantane, carbazole, dansyl and dabsyl, suitable for use in immunod

Hapten-phosphoramidites based on 6-[(2E)-N-(hexyl)prop-2-enamidyl]-2′-deoxyuridine

Novel hapten-phosphoramidites 11a-c were prepared from 2′-deoxyuridine (2) by functionalization at the 6-position and subsequent conjugation with adamantane, carbazole and dansyl reporter groups in good overall yield.