370595-50-9

Upstream product

• 34995-01-2 N-(6-aminohexyl)-5-dimethylamino-naphthalene-1-sulfonamide 
• 606126-53-8 1-N-dansyl-6-N-Boc-diaminohexane 
• 370595-45-2 (+)-6-[2-(methoxycarbonyl)ethenyl]-2'-deoxyuridine-3',5'-(1,1,3,3-tetraisopropyl)disiloxane 
• 370595-47-4 (+)-5'-O-(4,4'-dimethoxytrityl)-6-[2-(methoxycarbonyl)ethenyl]-2'-deoxyuridine 
• 370595-46-3 (+)-6-[2-(methoxycarbonyl)ethenyl]-2'-deoxyuridine 
• 149857-04-5 1-[3,5-Bis-O-(1,1,3,3-tetraisopropyldisilox-1,3-diyl)-2-deoxy-β-D-erythro-furanosyl]uracil-6-carboxaldehyde 
• 98495-56-8 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 951-78-0 2'-deoxyuridine 
• 605-65-2 5-(dimethylamino)naphth-1-ylsulfonyl chloride 
• 51857-17-1 tert-butyl N-(6-aminohexyl)carbamate 

Relevant academic research and scientific papers

Synthesis of hapten-phosphoramidites from 2′-deoxyuridine

A total of 11 novel phosphoramidites, 3a-d, 4a-d and 14a-c were prepared from 2′-deoxyuridine functionalized at 5 and 6-position of the pyrimidine ring with hapten reporter groups, e.g. adamantane, carbazole, dansyl and dabsyl, suitable for use in immunod

Hapten-phosphoramidites based on 6-[(2E)-N-(hexyl)prop-2-enamidyl]-2′-deoxyuridine

Novel hapten-phosphoramidites 11a-c were prepared from 2′-deoxyuridine (2) by functionalization at the 6-position and subsequent conjugation with adamantane, carbazole and dansyl reporter groups in good overall yield.