370839-63-7

Basic information

• Product Name: N,N-diphenylpyridine-2-sulfonamide
• Synonyms: N,N-diphenylpyridine-2-sulfonamide
• CAS NO: 370839-63-7
• Molecular Weight: 310.376
• Mol File: 370839-63-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N-diphenylpyridine-2-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diphenylpyridine-2-sulfonamide(370839-63-7)
• EPA Substance Registry System: N,N-diphenylpyridine-2-sulfonamide(370839-63-7)

Safety Data

• Hazardous Substances Data: 370839-63-7(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 1352965-24-2 N-methyl-N-phenylpyridine-2-sulfonamide 
• 66715-65-9 pyridine-2-sulfonyl chloride 
• 103863-00-9 N-Phenylpyridine-2-sulfonamide 
• 603-33-8 triphenylbismuthane 
• 62-53-3 aniline 

Downstream Products

• 50910-08-2 2-N,N-diphenylaminopyridine 
• 122-39-4 diphenylamine 

Relevant articles and documents

Nickel-Catalyzed Intramolecular Desulfitative C - N Coupling: A Synthesis of Aromatic Amines

A nickel-catalyzed intramolecular C - N coupling reaction via SO2 extrusion is presented. The use of a catalytic amount of BPh3 allows the transformation to take place under much milder conditions (60 °C) than previously reported C - N coupling reactions by CO or CO2 extrusion (160-180 °C). In addition, this method displays good functional group tolerance and versatility, as it can be applied to the synthesis of dialkyl aryl amines, alkyl diaryl amines, and triaryl amines. The robustness of the desulfitative C - N coupling is demonstrated by three high-yielding gram-scale reactions.

Deprotection of 2-pyridyl sulfonyl group from pyridine-2-sulfonamides by magnesium in methanol

Convenient deprotection of various pyridine-2-sulfonamides prepared by sulfonylation of primary and secondary amines with pyridine-2-sulfonylchloride was achieved by magnesium in methanol at 0°C to the corresponding amines in good yield.