37095-27-5

Basic information

• Product Name: [mu-Bis(diphenylphosphino)methane]dichlorodigold(III),99%
• Synonyms: [μ-Bis(diphenylphosphino)methane]dichlorodigold(I),98%;(DPPM)(AuCl)2;Bis(chlorogold) bis(diphenylphosphino)methane;[mu-Bis(diphenylphosphino)methane]dichlorodigold(III),99%;[μ-Bis(diphenylphosphino) methane]dichlorodigold(I), 99%;[Mu-Bis(diphenylphosphino)Methane]dichlorodigold(III);[mu-Bis(diphenylphosphino)methane]dichlorodigold(I), 99%;[Mu-Bis(diphenylphosphino)Methane]dichlorodigold(I),99%
• CAS NO: 37095-27-5
• Molecular Formula: C₂₅H₂₂Au₂Cl₂P₂
• Molecular Weight: 849.243
• Product Categories: Au;organometallic complex
• Mol File: 37095-27-5.mol
• Article Data: 16

Chemical Properties

• Melting Point: 271-272℃
• Appearance: white/Powder
• CAS DataBase Reference: [mu-Bis(diphenylphosphino)methane]dichlorodigold(III),99%(CAS DataBase Reference)
• NIST Chemistry Reference: [mu-Bis(diphenylphosphino)methane]dichlorodigold(III),99%(37095-27-5)
• EPA Substance Registry System: [mu-Bis(diphenylphosphino)methane]dichlorodigold(III),99%(37095-27-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 37095-27-5(Hazardous Substances Data)

Usage

Reactions

Catalyst used with chiral counter-ion for asymmetric hydroalkoxylation. Catalyst used for intramolecular acetylene Schmidt reaction.

Uses

Used for Pharmacological studies involving the anticancer activity of gold(I)-phosphine complexes as autophagy-inducing agentsTriplet luminescent light emitting diodes with low turn-on voltageCatalyst for:Stereoselective preparation of vinyltetrahydrofuran via intramolecular hydroalkoxylationHydroamination and hydroalkoxylation reactionsAsymmetric transition metal catalysisGold(I) catalyzed intramolecular Schmidt reactions of homopropargyl azides

Upstream product

• 39929-21-0 (tetrahydrothiophene)gold(I) chloride 
• 2071-20-7 bis-diphenylphosphinomethane 
• 41867-99-6 diethyl sulfide gold chloride 
• 64345-29-5 {PdCl(μ-dppm)}2 
• 111-48-8 2,2'-thiobis-ethanol 
• 29892-37-3 chloro(dimethylsulfide) gold(I) 
• 110790-43-7 {PdPtCl2(μ-dppm)2} 
• 106402-58-8 bis(triphenylphosphine)nitrogen gold dichloride 
• 64345-29-5 [Pd2Cl2(μ-bis(diphenylphosphino)methane)2] 

Downstream Products

• 64645-30-3 (AuCl)2(μ-cis-1,2-bis(diphenylphosphino)ethylene) 
• 158701-20-3 [Au₂(CH₂(P(C₆H₅)2)2)(C₆H₅)2] 
• 63356-91-2 [Au₂(CH₂(P(C₆H₅)2)2)(CH₃)2] 
• 79747-46-9 {(1,1-bis(diphenylphosphino)methane)Au2}(μ-2,2'-bibenzimidazolato) 
• 88206-20-6 Au((P(C₆H₅)2CH₂P(C₆H₅)2)ClAu)2⁽¹⁺⁾*ClO₄^(1-)=Au((P(C₆H₅)2CH₂P(C₆H₅)2)ClAu)2ClO₄ 
• 55172-29-7 thallium chloride 
• 429-06-1 N,N,N,N-tetraethylammonium tetrafluoroborate 
• 185520-10-9 [Au2(μ-1,2-dithiolate-o-carborane)(μ-dppm)] 

Relevant articles and documents

Homo- And hetero-metallophilicity-driven synthesis of highly emissive and stimuli-responsive Au(i)-Cu(i) double salts

Complex salts composed of cationic Au(i) and anionic Cu(i) species were synthesized by utilizing bis(diphenylarsino)methane (dpam) and bis(diphenylphosphino)methane (dppm) ligands. The discrete tetranuclear complexes were obtained as crystals, and the four-metal chain, Cu?Au?Au?Cu, was linked through homo- and hetero-metallophilic interactions. Three crystal polymorphs were obtained for the dpam- and dppm-complexes, depending on the recrystallization solvent. All the crystals exhibited intense phosphorescence (quantum yields up to 0.97) at room temperature, and the emission color of each crystal was significantly different. The crystals could be interconverted by exposure to solvent vapor, and this was accompanied by a drastic change in the emission color.

Exceptionally fast carbon-carbon bond reductive elimination from gold(III)

Reductive elimination of carbon-carbon bonds occurs in numerous metal-catalysed reactions. This process is well documented for a variety of transition metal complexes. However, carbon-carbon bond reductive elimination from a limited number of Au(III) complexes has been shown to be a slow and prohibitive process that generally requires elevated temperatures. Herein we show that oxidation of a series of mono- and bimetallic Au(I) aryl complexes at low temperature generates observable Au(III) and Au(II) intermediates. We also show that aryl-aryl bond reductive elimination from these oxidized species is not only among the fastest observed for any transition metal, but is also mechanistically distinct from previously studied alkyl-alkyl and aryl-alkyl reductive eliminations from Au(III).

Synthesis, structures and anti-malaria activity of some gold(i) phosphine complexes containing seleno- and thiosemicarbazonato ligands

A series of both mono- and dinuclear gold(i) phosphine complexes containing monoanionic seleno- and thiosemicarbazones as ligands were prepared and fully characterized by spectroscopic methods and, in some cases, by single crystal X-ray diffraction. The in vitro anti-malaria activity of some of these compounds was investigated in chloroquine sensitive strains of Plasmodium falciparum. The IC50 results show that the sulfur containing compounds exhibit activity similar to that of chloroquine, whilst the selenium derivatives display only moderate anti-malaria activity.