37095-43-5

Usage

Uses

Used in Scientific Research:
5,10,15,20-Tetrakis(4-fluorophenyl)-21H,23H-porphine is used as a research chemical for studying its properties and potential applications. Its distinctive characteristics make it a valuable compound in various scientific studies.
Used in Photodynamic Therapy:
In the medical field, 5,10,15,20-Tetrakis(4-fluorophenyl)-21H,23H-porphine is used as a photosensitizer in photodynamic therapy. It is employed for its light-absorbing properties, which allow it to generate reactive oxygen species upon light exposure, leading to the destruction of targeted cells, such as cancer cells.
Used in Material Science:
5,10,15,20-Tetrakis(4-fluorophenyl)-21H,23H-porphine is used as a component in the development of advanced materials, such as organic semiconductors and sensors, due to its unique electronic and photophysical properties. Its incorporation can enhance the performance of these materials in various applications, including electronics and sensing technologies.

InChI:InChI=1/C44H26F4N4/c45-29-9-1-25(2-10-29)41-33-17-19-35(49-33)42(26-3-11-30(46)12-4-26)37-21-23-39(51-37)44(28-7-15-32(48)16-8-28)40-24-22-38(52-40)43(36-20-18-34(41)50-36)27-5-13-31(47)14-6-27/h1-24,49,52H/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 221247-13-8 2,2'-((4-fluorophenyl)methylene)bis(1H-pyrrole) 
• 22112-84-1 tetrakis(4-aminophenyl)porphyrin 
• 109-97-7 pyrrole 

Downstream Products

• 76500-30-6 Ag(p-FTPP) 
• 60430-20-8 CoN₄C₂₀H₈(C₆H₄F)4 
• 60250-84-2 5,10,15,20-tetra(4-fluorophenyl) porphyrinato manganese chloride 
• 60250-94-4 (tetrakis(4-fluorophenyl)porphyrinato)zinc(II) 
• 189701-27-7 meso-tetra(4-chlorophenyl)porphyrinatoaluminum chloride 
• 1246928-78-8 C₄₄H₂₄F₄N₄Rh⁽¹⁺⁾*Cl^(1-) 

Relevant academic research and scientific papers

Molecular structure of 5,10,15,20-tetrakis(4′-fluorophenyl)porphyrin by combined gas-phase electron diffraction/mass spectrometry experiment and DFT calculations

Molecular parameters of 5,10,15,20-tetrakis(4′-fluorophenyl)porphyrin were determined for the first time by gas-phase electron diffraction. Conformational preference was investigated based on the experimental data and was found to be in the good agreement

Efficient oxidation of cycloalkanes with simultaneously increased conversion and selectivity using O2 catalyzed by metalloporphyrins and boosted by Zn(AcO)2: A practical strategy to inhibit the formation of aliphatic diacids

The direct sources of aliphatic acids in cycloalkanes oxidation were investigated, and a strategy to suppress the formation of aliphatic acids was adopted through enhancing the catalytic transformation of oxidation intermediates cycloalkyl hydroperoxides to cycloalkanols by Zn(II) and delaying the emergence of cycloalkanones. Benefitted from the delayed formation of cycloalkanones and suppressed non-selective thermal decomposition of cycloalkyl hydroperoxides, the conversion of cycloalkanes and selectivity towards cycloalkanols and cycloalkanones were increased simultaneously with satisfying tolerance to both of metalloporphyrins and substrates. For cyclohexane, the selectivity towards KA-oil was increased from 80.1% to 96.9% meanwhile the conversion was increased from 3.83 % to 6.53 %, a very competitive conversion level with higher selectivity compared with current industrial process. This protocol is not only a valuable strategy to overcome the problems of low conversion and low selectivity lying in front of current cyclohexane oxidation in industry, but also an important reference to other alkanes oxidation.

UV–visible and fluorescence spectroscopic assessment of meso?tetrakis?(4?halophenyl) porphyrin; H2TXPP (X = F, Cl, Br, I) in THF and THF-water system: Effect of pH and aggregation behaviour

The current study determines optical and fluorescence response of halogen substituted series of meso?tetrakis?(4?halophenyl) porphyrin; H2TXPP (Halo = F, Cl, Br, I) dye in tetrahydrofuran; THF and THF-water system at changing pH in relationship with changing medium of allure. Effects produced by varying the pH and medium, over spectral and aggregation were discussed in detail. Results show sequential protonation and deprotonation of H2TXPP series in acidic (pH = 4) and (pH =10) basic medium. Specific structural changes of monomeric absorption band were put in evidence on lowering pH, which includes broadening and splitting of soret or B band. Other changes include increasing in intensity and red-shifting of Q1 band indicating some degree of aggregation. The side-by-side aggregation and formation of J-aggregate were quite evident. The red shift of B band featured self-aggregation through head-to-tail molecular ordering which is consonant with absorption-emission data.

A four-phenyl porphine preparation method

The invention discloses a preparation method of meso-tetraphenylchlorin. The preparation method comprises the steps that 1, a mixed solution of pyrrole and aromatic aldehyde is prepared for standby; 2, a solvent is added into a polymerization reactor, nitrogen displacement is conducted till the concentration of tail oxygen is lower than 1%, the solvent is heated to backflow, the mixed solution obtained in the first step starts to be dropwise added, a reaction is started, after the mixed solution is dropwise added completely, the reaction is continuously conducted for 0.05 h to 0.5 h, and then the reaction is stopped; 3, oxygen-containing gas with the oxygen volume fraction ranging from 5% to 100% is fed into the polymerization reactor for oxidation, cooling is conducted after the oxidation is completed, filtration is conducted to obtain a filter cake and filtrate, and a product is obtained after the filter cake is washed and dried. The preparation method of the meso-tetraphenylchlorin has the advantages that the yield is high, safety and environmental protection are achieved, separation and purification are easy, and the product quality is stable.

A four-phenyl porphine production method (by machine translation)

The invention discloses a production method for tetraphenyl porphin. The production method includes the steps that 1, pyrrole and aromatic aldehyde are prepared into a mixed solution for standby application; 2, solvent is added into a polymerization reactor, the pressure of the polymerization reactor is maintained at 1-5 atm, the mixed solution obtained in the step 1 starts to be dripped to start a polymerization reaction, after the reaction is finished, reaction products are cooled to normal temperature, and filter liquor and a filter cake are obtained through filtration; 3, the filter cake obtained in the step 2 and propionic acid are added into an oxidation reactor, oxygen-containing gas is introduced to carry out an oxidation reaction, cooling is carried out after oxidation is finished, a solid and filter liquor are obtained through filtration, and the solid is washed and dried to obtain the tetraphenyl porphin. The production method has the advantages of being high in yield, safe and environmentally friendly, separation and purification are easy, and the production quality is stable.

Synthesis of novel single site tin porphyrin complexes and the catalytic activity of tin tetrakis(4-fluorophenyl)porphyrin over -caprolactone

Tin tetrakis(4-fluorophenyl)porphyrin, tin tetrakis(4-chlorophenyl)porphyrin and tin tetrakis(4-bromophenyl)porphyrin complexes were prepared by reaction of butyltin trichloride with tetrakis(4-fluorophenyl)porphyrin, tetrakis(4-chlorophenyl)porphyrin, and tetrakis(4-bromophenyl)porphyrin in tetrahydrofuran and toluene, respectively. These novel complexes were characterized by 1H, 13C NMR, FTIR, mass spectroscopy and elemental analysis. The single site tin complex including fluoride was tested as a catalyst in polymerization of -caprolactone and was very effective. Polycaprolactone was characterized by 1H, 13C NMR, and gel permeation chromatography.

Microwave-Assisted synthesis of fluorine substituted porphyrins and kinetics of formation of zinc porphyrin complexes in acetic acid

Three mono-fluorine substituted porphyrin compouds were synthesized under microwave irradiation. The effects of catalysts and oxidants on the yields of mono-fluorine substituted porphyrins also were investigated. The yields of 5,10,15,20-tetrakis(4-fluoro

An aluminum porphyrin complex with high activity and selectivity for cyclic carbonate synthesis

An aluminum porphyrin complex with a quaternary ammonium salt cocatalyst exhibits high activity (i.e., a turnover frequency as high as 1.85 × 105 h-1) and selectivity (>99%) for cyclic carbonates synthesis from CO2 and epoxides; the catalyst can be reused at least 4 times with only a slight loss in activity.

Mono-oxido-bridged heterobimetallic and heterotrimetallic compounds containing titanium(IV) and chromium(III)

A series of oxido-bridged heterobi- and heterotrimetallic complexes, [(tmtaa)Ti=O→Cr(Por)Cl] and [(tmtaa)Ti=O→Cr(Por)←O=Ti(tmtaa)]+ (tmtaa = 7,16-dihydro-6,8,15,17-tetramethyldibenzo[b,i][1,4,8,11]tetraazacyclotetradecine; Por = 5,10,15,20-tetr

Ecofriendly Porphyrin Synthesis by using Water under Microwave Irradiation

Water, under microwave irradiation and at a temperature of 473 K, reaches pressures above 16 bar, being capable to act as catalyst, without the use of organic solvents and oxidants, for meso-substituted porphyrin synthesis. Sustainability of the reaction is proved by E Factor=35 and EcoScale value of 50.5, the highest so far obtained for porphyrin synthesis. Methodology's wide versatility is clearly demonstrated by the good yields obtained for both aryl and alkyl substituted porphyrins. These reaction conditions represent a huge development, not only by using very high concentrations, minimizing organic solvent usage, but also by eradicating toxic expensive solvents and oxidants.