371165-45-6

Basic information

• Product Name: C₁₇H₁₅ClN₂O
• Synonyms: C₁₇H₁₅ClN₂O
• CAS NO: 371165-45-6
• Molecular Weight: 298.772
• Mol File: 371165-45-6.mol
• Article Data: 3

Chemical Properties

• Density: 1.23±0.1 g/cm3(Predicted)
• CAS DataBase Reference: C₁₇H₁₅ClN₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₅ClN₂O(371165-45-6)
• EPA Substance Registry System: C₁₇H₁₅ClN₂O(371165-45-6)

Safety Data

• Hazardous Substances Data: 371165-45-6(Hazardous Substances Data)

Upstream product

• 7559-36-6 4-methyl-β-nitrostyrene 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 1381932-38-2 C₁₅H₁₇NO₆ 
• 193979-47-4 ethyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate 
• 189005-44-5 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid 

Downstream Products

• 365213-58-7 2-(4-methylphenyl)-6-methylimidazo[1,2-α]pyridine-3-acetamide 
• 82644-31-3 N-methyl-2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetamide 
• 82626-48-0 N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide 

Relevant articles and documents

Synthesis of imidazopyridines from the Morita-Baylis-Hillman acetates of nitroalkenes and convenient access to alpidem and zolpidem

A variety of functionalized imidazo[1,2-a]pyridines have been synthesized through a one-pot, room temperature, and reagent-free reaction between MBH acetates of nitroalkenes and 2-aminopyridines. The reaction involves a cascade inter-intramolecular double aza-Michael addition of 2-aminopyridines to MBH acetates. Our methodology is marked by excellent yield, regioselectivity and, above all, adaptability to synthesize imidazopyridine-based drug molecules such as Alpidem and Zolpidem.

Processes for the preparation of imidazo[1,2-a] pyridine derivatives

A process for the preparation of imidazo[1,2-a]pyridine derivatives of the formula I: wherein R is hydrogen, halogen or a C1-C4 alkyl group; R1 and R2 are independently hydrogen, a straight or branched C1/