82644-31-3Relevant academic research and scientific papers
Metal-Free Approach to Zolpidem, Alpidem and their Analogues via Amination of Dibromoalkenes Derived from Imidazopyridine and Imidazothiazole
Muzalevskiy, Vasiliy M.,Sizova, Zoia A.,Shastin, Alexey V.,Nenajdenko, Valentine G.
, p. 4034 - 4042 (2019/06/24)
A novel efficient approach towards Zolpidem, Alpidem and their analogues was elaborated. The corresponding amides derived from imidazopyridine and imidazothiazole were prepared by the reaction of amines with previously unknown dibromoalkenes having these heterocyclic fragments. Amination of dibromoalkenes in the presence of water led directly to target drugs and their analogues in up to 95 % yield.
PROCESS FOR PREPARING ZOLPIDEM
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Page/Page column title page; sheet 1; 6-7, (2010/11/25)
A process for preparing zolpidem.
