3717-20-2

Upstream product

• 3848-34-8 4-nitro-benzaldehyde-(O-acetyl-seqcis-oxime ) 
• 1129-37-9 4-nitrobenzaldehyde oxime 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 555-16-8 4-nitrobenzaldehdye 
• 2017-89-2 (E)-ethyl 2-cyano-3-(4-nitrophenyl)acrylate 
• 136427-82-2 C₁₂H₁₃N₃O₃S₂ 
• 71-43-2 benzene 

Downstream Products

• 50998-71-5 4-nitro-benzaldehyde-(N-allyl oxime ) 
• 3419-18-9 4-aminobenzaldehyde oxime 
• 555-16-8 4-nitrobenzaldehdye 
• 619-72-7 4-nitrobenzonitrile 
• 3848-34-8 4-nitro-benzaldehyde-(O-acetyl-seqcis-oxime ) 
• 25387-13-7 3-hydroxy-2-(4-nitro-phenyl)-4-trichloromethyl-[1,3]oxazinan-6-one 
• 3419-18-9 p-Amino-benzaldoxim 
• 13676-47-6 5-amino-2-(4'-aminophenyl)-benzoxazole 
• 1037-39-4 2-(4-nitrophenyl)-5-nitrobenzoxazole 
• 75800-84-9 Z-O-methyl-p-nitrobenzaldoxime 
• 16089-71-7 (Z)-N-(4-nitrobenzylidene)methylamine N-oxide 
• 4403-71-8 (4-aminomethyl)aniline 
• 122-85-0 para-acetamidobenzaldehyde 
• 110853-54-8 (E)-N-[4-[hydroxyiminomethyl]phenyl]acetamide 

Relevant academic research and scientific papers

Preparation method O - alkyl substituted hydroxylamine salt

The invention relates to a preparation method of N - alkyl substituted hydroxylamine salt, and belongs to fine chemical engineering. Pesticide or bulk pharmaceutical chemicals technical field. The present invention reacts with the N - alkyl of the oxime with an inorganic salt of hydroxylamine to give N - alkyl-substituted hydroxylamine salt and oxime. The invention provides an efficient and environment-friendly method for preparing N - alkyl substituted hydroxylamine salt, and simultaneously, an N - alkyl substituted hydroxylamine salt is prepared, and the oxime can be re-prepared to form N - alkylate of oxime so as to realize the material circulation. No equivalent acid is used in the reaction process. Alkali neutralization, avoided the current method to use a large amount of acid, alkali and produce inorganic salt solid waste shortcoming, environmental protection more. The preparation method is mild in reaction condition, and the defects of high pollution and high energy consumption of the traditional process are overcome. In-flight R1 , R2 What is R is as claimed in the claims and the description.

Annulation of Oxime-Ether Tethered Donor–Acceptor Cyclopropanes

Novel oxime-ether tethered cyclopropanes, when exposed to Yb(OTf)3 and heat, annulate to generate hydropyrrolo-oxazines products that can be taken to their respective pyrrolidines via hydrogenative N?O bond cleavage. The hydropyrrolo-oxazines are generated in a diastereoselective manner isolating the cis or trans product based on the temperature of the reaction. 20 examples of selective cis and trans hydropyrrolo-oxazines were generated in high yields by temperature control.

Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase

Stereoselective aldoximes, preferably Z form have been obtained from α-cyano substituted carbonyl conjugated alkenes. This reaction occurs through Michael addition type reaction followed by retro-Knoevenagel reaction without transition-metal catalysis via C–C bond cleavage. These oximes are evaluated against cancer cell lines employing mechanistic study. Two oximes showed significant cytotoxic activity, which through in silico studies were found to inhibit MRCK Kinase, responsible for metastatic spread of cancer mortality.

Host (dealuminated Y zeolite)–guest (zirconium tetraphenylporphyrin) nanocomposite materials. An efficient catalyst in the oximation of aldehydes

In this research, zirconium tetraphenylporphyrin encapsulated into dealuminated Y zeolite (ZrTPP–DAZY) was prepared through a template synthesis method. This heterogeneous catalyst was characterized by XRD, FT-IR, DRS, UV–Vis, EDX and FESEM techniques. The amount of ZrTPP in the nanocage of dealuminated Y zeolite was estimated to be 0.0156?g/g of support. This catalytic system was employed for an efficient oximation of aldehydes under magnetic stirring conditions at room temperature and the corresponding products were obtained in 50–90% yields. This catalytic system also indicated good shape selectivity towards linear aldehydes. ZrTPP–DAZY was reused several times without any significant loss in catalytic activity.

METHOD FOR PRODUCING ALDOXIME COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing an aldoxime compound using no expensive catalysts and reagents and also requiring no severe reaction conditions. SOLUTION: There is provided a method for producing an aldoxime compound containing a process where an aldehyde compound and an oxime compound are brought into trans oximation reaction in the presence of perchloric acid and/or the metallic salt of perchloric acid in an organic solvent and water. The metallic salt of perchloric acid is preferably ferric perchlorate, cobalt perchlorate, nickel perchlorate, zinc perchlorate, aluminum perchlorate or calcium perchlorate. Also, the organic solvent is preferably methylene chloride and/or ethylene dichloride. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

NH2OH.HCl/BaCl2: A convenient system for synthesis of oximes from the corresponding of organic carbonyl compounds

A variety of aldehydes and ketones were converted to their corresponding oximes NH2OH·HCl/BaCl2 system in reflux conditions.

Synthesis of oximes with NH2OH.HCl/DOWEX(R)50WX4 system

The oximation of a variety of carbonyl compounds was efficiently carried out with DOWEX(R)50WX4/NH2OH·HCl system. The reactions were performed in ethanol to give Z-aldoximation isomers of aldehydes and E-oximaton of acetophenone derivatives in a perfect selectively. The oximation of compounds with two carbonyl groups was carried out selectively on one carbonyl moiety. Also, the oximation of aldehydes over ketones has been accomplished successfully by this system.

Catalytic performance of preyssler anion in selective oximation of aromatic aldehydes

Preyssler catalyst, H14[NaP5W30O110], catalyzes the aldoximation of aromatic aldehydes for the synthesis of Z-isomers in conventional manner and under microwave irradiation. Both pure acid and silica-supported catalysts were used and their activities compared with common catalysts such as K2CO3 and CuSO4. The Preyssler is the catalyst for this reaction.

AlPW12O40 and AlPMo12O40 as highly effective and eco-friendly catalysts for aldoximation of aldehydes under solvent-free conditions

The oxime formation of aromatic aldehydes has directly been carried out with hydroxylamine hydrochloride using heteropoly acids (AlPW12O 40, AlPMo12O40) as catalysts in the absence of solvent. It is found that these heteropoly acids were effective catalysts for the formation of oxime of aldehydes. This method consistently has the advantage of high yields of the products, short reaction time, mild and solvent-free conditions, cleaner reactions and isolation procedures.

Alumina sulfuric acid mediated solvent-free and one-step Beckmann rearrangement of ketones and aldehydes and a useful reagent for synthesis of keto- and ald-oximes

Under solvent-free conditions, one-step Beckmann rearrangement of a variety of ketones and aldehydes could proceed in the presence of alumina sulfuric acid (ASA). The ASA reagent can also be used for the preparation of keto- and ald-oximes.