3717-44-0

Usage

Uses

Used in Pharmaceutical Industry:
N-ethyl-1-adamantanamine is used as an antiviral agent for its potential to combat viral infections, leveraging its unique structure and pharmacological properties to interfere with viral replication processes.
Used in Neurological Treatments:
In the field of neurology, n-ethyl-1-adamantanamine is utilized as an antiparkinsonian agent, targeting the symptoms and progression of Parkinson's disease by potentially modulating neurotransmitter levels or enhancing neuronal function.
Used in Drug Synthesis:
N-ethyl-1-adamantanamine serves as a valuable precursor in the synthesis of other organic compounds, contributing to the development of new pharmaceuticals and chemical products.
Used in Addiction Treatment:
n-ethyl-1-adamantanamin is explored for its potential use in treating drug addiction, possibly through its interaction with the brain's reward system or by mitigating withdrawal symptoms, aiding in the rehabilitation process.
Used in Neuroprotection:
N-ethyl-1-adamantanamine is investigated for its neuroprotective properties, which may help in preserving neuronal function and integrity, particularly in conditions associated with neurodegeneration.

InChI:InChI=1/C12H21N/c1-2-13-12-6-9-3-10(7-12)5-11(4-9)8-12/h9-11,13H,2-8H2,1H3

Upstream product

• 34913-37-6 N-Chlor-N-aethyl-1-adamantanamin 
• 768-94-5 1-Adamantanamine 
• 64-19-7 acetic acid 

Relevant academic research and scientific papers

Catalytic N-Alkylation of Amines Using Carboxylic Acids and Molecular Hydrogen

A convenient, practical and green N-alkylation of amines has been accomplished by applying readily available carboxylic acids in the presence of molecular hydrogen. Applying an in situ formed ruthenium/triphos complex and an organic acid as cocatalyst, a broad range of alkylated secondary and tertiary amines are obtained in good to excellent yields. This novel method is also successfully applied for the synthesis of unsymmetrically substituted N-methyl/alkyl anilines through a direct three-component coupling reaction of the corresponding amines, carboxylic acids, and CO2 as a C1 source.

Thermolysis of N,N-Dihalo Derivatives of Bridgehead and Neopentylamines to the Corresponding Halides.

N,N-Dihalo derivatives of (1-adamantyl)- and neopentylamine are converted to the corresponding alkyl halides in excellent yields (88-94percent) during GLC at 155-330 deg C.Decomposition apparently occurs by an SNi mechanism or by intramolecular homolytic cleavage.Intermolecular radical and free-ion reactions are eliminated from consideration because of the absence of radical-derived or rearranged products.Steric factors are deemed important in the neopentyl case since pyrolysis of N,N-dihaloamine gave the corresponding carbonitrile in excellent yield(90-97percent). 1-(Haloamino)adamantanes gave fair amounts of 1-haloadamantanes (30-38percent). 1-(Acetylamino)- and 1-(ethylchloroamino)adamantane yielded 1-chloroadamantane (10-17percent), the major products being the acetamide (60percent) and the ethylamine (56percent), respectively. 1-(Dihaloamino)adamantanes were converted to 1-haloadamantanes by neat (64-70percent) or solution (30-41percent) pyrolysis.