372193-58-3

Usage

Properties

Boronic acid derivative containing an allyl group and a phenyl ring

Uses

Commonly used as a reagent in organic chemistry for various synthetic transformations, especially in the formation of carbon-carbon bonds

Ability

Known for its ability to form stable complexes with a wide range of substrates

Applications

Used in the development of pharmaceuticals, agrochemicals, and materials science for its versatile reactivity and potential for creating unique structures

Upstream product

• 42918-20-7 1-allyl-2-bromobenzene 
• 5419-55-6 Triisopropyl borate 
• 890053-90-4 dimethyl 2-allylphenylboronate 
• 857934-92-0 4,4,5,5-tetramethyl-2-[2-(2-propenyl)phenyl]-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Meta-Selective C-H Borylation of Benzamides and Pyridines by an Iridium-Lewis Acid Bifunctional Catalyst

We report herein the iridium-catalyzed meta-selective C-H borylation of benzamides by using a newly designed 2,2′-bipyridine (bpy) ligand bearing an alkylaluminum biphenoxide moiety. We also demonstrate the iridium-catalyzed C3-selective C-H borylation of pyridine with a 1,10-phenanthroline (Phen) ligand bearing an alkylborane moiety. It is proposed that the Lewis acid-base interaction between the Lewis acid moiety and the aminocarbonyl group or the sp2-hybridized nitrogen atom accelerates the reaction and controls the site-selectivity.

Synthesis of 6,7-benzo-3-borabicyclo[3.3.1]nonane and its 3-aza analog from 2-allylphenyl(diallyl)borane. Intramolecular arylboration of the C=C bond

A method was developed for the synthesis of 6,7-benzo-3-borabicyclo[3.3.1] nonane and 6,7-benzo-3-azabicyclo[3.3.1]nonane derivatives based on intramolecular cyclization of 2-allylphenyl(diallyl)borane. Intramolecular arylboration of the double bond in 1,

Bromo-boronolactonization of olefins

Exposure of a variety of mono- and disubstituted ortho-alkenylarylboronic acids to NBS in THF/H2O under neutral conditions affords bromo-boronolactones, in some instances, with exceptional regiocontrol. The adducts, analogous to those formed by carboxylic acids, are shown to be useful synthetic intermediates.