3725-11-9

Basic information

• Product Name: Cyclohexanemethanol, 4-methylbenzenesulfonate
• CAS NO: 3725-11-9
• Molecular Formula: C14H20O3S
• Molecular Weight: 268.377
• Mol File: 3725-11-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Cyclohexanemethanol, 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, 4-methylbenzenesulfonate(3725-11-9)
• EPA Substance Registry System: Cyclohexanemethanol, 4-methylbenzenesulfonate(3725-11-9)

Safety Data

• Hazardous Substances Data: 3725-11-9(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 100-49-2 cyclohexylmethyl alcohol 
• 4630-82-4 methyl cyclohexylcarboxylate 

Downstream Products

• 53973-68-5 cyclohexylmethyl phenyl selenide 
• 53973-70-9 Cyclohexylmethyl-o-nitrophenylselenid 
• 53973-69-6 Cyclohexylmethyl-p-chlorphenylselenid 
• 109954-02-1 (2-Cyclohexylmethoxy-5-decyl-phenyl)-phosphonic acid diethyl ester 
• 5469-33-0 cyclohexylmethyl iodide 
• 81917-06-8 (azidomethyl)cyclohexane 
• 1192-37-6 methylenecyclohexane 
• 14962-20-0 4-(1-methylcyclohexyl)phenol 
• 177963-04-1 ((S)-2-Azido-1-cyclohexylmethoxy-ethyl)-benzene 
• 177963-08-5 4-((R)-2-Azido-1-cyclohexylmethoxy-ethyl)-1,2-bis-benzyloxy-benzene 
• 19752-94-4 cyclohexylmethanol methyl ether 
• 104-15-4 toluene-4-sulfonic acid 
• 127660-88-2 N-(Cyclohexylmethyl)-N-(p-tolyl)amine 
• 14034-62-9 4-methylanilinium p-toluenesulfonate 

Relevant articles and documents

Titanium(III)-Catalyzed Reductive Decyanation of Geminal Dinitriles by a Non-Free-Radical Mechanism

A titanium-catalyzed mono-decyanation of geminal dinitriles is reported. The reaction proceeds under mild conditions, tolerates numerous functional groups, and can be applied to quaternary malononitriles. A corresponding desulfonylation is demonstrated as well. Mechanistic experiments support a catalyst-controlled cleavage without the formation of free radicals, which is in sharp contrast to traditional stoichiometric radical decyanations. The involvement of two TiIII species in the C?C cleavage is proposed, and the beneficial role of added ZnCl2 and 2,4,6-collidine hydrochloride is investigated.

Preparation method of bromomethylcyclohexane

The invention relates to a preparation method of bromomethylcyclohexane. The method comprises the steps that 1, alkali and cyclohexylmethanol are added into an organic solvent, then a compound in theformula (I) shown in the description is added dropwise, and esterification is conducted to obtain an organic-phase intermediate filtrate, wherein R is C1-12 alkyl or C1-12 halogen alkyl or C3-8 naphthenic base or phenyl or benzyl or aromatic hydrocarbon, X is a halogen atom, and the molar radio of the cyclohexylmethanol to the compound in the formula (I) is 1:1-1:2; 2, a bromide and a crown ethercatalyst are added into the obtained organic-phase intermediate filtrate for bromination reaction to obtain reaction liquid, then through filtering, abraum salt is removed, through rectification, a crude bromomethylcyclohexane product is obtained, and then through drying, a finished bromomethylcyclohexane product is obtained. The method has the advantages that high-salinity wastewater is reduced,reaction time is shortened, the reaction rate is improved, the production cost is reduced, and the product yield is improved.

Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate

We report an expansion of the structure-activity relationship (SAR) of a novel series of indole-3-heterocyclic CB1 receptor agonists. Starting from the potent but poorly soluble lead, 1, a rational approach was taken in order to balance solubility, hERG a