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(R)-methyl 2-amino-3-(4-iodophenyl)propanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 372967-43-6 Structure
  • Basic information

    1. Product Name: (R)-methyl 2-amino-3-(4-iodophenyl)propanoate
    2. Synonyms: (R)-methyl 2-amino-3-(4-iodophenyl)propanoate
    3. CAS NO:372967-43-6
    4. Molecular Formula:
    5. Molecular Weight: 305.115
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 372967-43-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-methyl 2-amino-3-(4-iodophenyl)propanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-methyl 2-amino-3-(4-iodophenyl)propanoate(372967-43-6)
    11. EPA Substance Registry System: (R)-methyl 2-amino-3-(4-iodophenyl)propanoate(372967-43-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 372967-43-6(Hazardous Substances Data)

372967-43-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 372967-43-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,2,9,6 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 372967-43:
(8*3)+(7*7)+(6*2)+(5*9)+(4*6)+(3*7)+(2*4)+(1*3)=186
186 % 10 = 6
So 372967-43-6 is a valid CAS Registry Number.

372967-43-6Relevant articles and documents

Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library

Leimbacher, Markus,Zhang, Yixin,Mannocci, Luca,Stravs, Michael,Geppert, Tim,Scheuermann, Jcrg,Schneider, Gisbert,Neri, Dario

supporting information; experimental part, p. 7729 - 7737 (2012/09/07)

Libraries of chemical compounds individually coupled to encoding DNA tags (DNA-encoded chemical libraries) hold promise to facilitate exceptionally efficient ligand discovery. We constructed a high-quality DNAencoded chemical library comprising 30 000 drug-like compounds; this was screened in 170 different affinity capture experiments. High-throughput sequencing allowed the evaluation of 120 million DNA codes for a systematic analysis of selection strategies and statistically robust identification of binding molecules. Selections performed against the tumor-associated antigen carbonic anhydrase IX (CA IX) and the pro-inflammatory cytokine interleukin-2 (IL-2) yielded potent inhibitors with exquisite target specificity. The binding mode of the revealed pharmacophore against IL-2 was confirmed by molecular docking. Our findings suggest that DNA-encoded chemical libraries allow the facile identification of drug-like ligands principally to any protein of choice, including molecules capable of disrupting high-affinity protein-protein interactions.

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