373826-71-2Relevant academic research and scientific papers
Synthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists
Johnson, Sigmond G.,Gunnet, Joseph W.,Moore, John B.,Miller, William,Wines, Pam,Rivero, Ralph A.,Combs, Don,Demarest, Keith T.
, p. 3362 - 3366 (2006)
A series of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives were synthesized as motilin receptor antagonists. Starting from known motilin antagonists, 1a and 1b, the cyclopentene scaffold was replaced and the four recognition elements optimi
