41171-91-9

Basic information

• Product Name: 3-Oxo-cyclopentanecarbonitrile
• Synonyms: 3-Oxo-cyclopentanecarbonitrile;3-Oxocyclopentane-1-Carbonitrile
• CAS NO: 41171-91-9
• Molecular Formula: C₆H₇NO
• Molecular Weight: 109.12588
• Mol File: 41171-91-9.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 250-270 °C(Press: 1 Torr)
• Appearance: /
• Density: 1.08±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Oxo-cyclopentanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxo-cyclopentanecarbonitrile(41171-91-9)
• EPA Substance Registry System: 3-Oxo-cyclopentanecarbonitrile(41171-91-9)

Safety Data

• Hazardous Substances Data: 41171-91-9(Hazardous Substances Data)

Usage

Uses

3-Cyanocyclopentanone is used for catalytic enantioselective conjugate addition of cyanide to enones.

Definition

ChEBI: An alicyclic ketone that is cyclopentanone substituted at position 3 by a cyano group.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 3455, 1973 DOI: 10.1021/jo00960a002

Upstream product

• 15760-35-7 3-methylenecyclobutanecarbonitrile 
• 930-30-3 cyclopent-2-enone 
• 7677-24-9 trimethylsilyl cyanide 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 120-92-3 cyclopentanone 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 151-50-8 potassium cyanide 
• 98098-46-5 3-cyano-1-diethylphosphonooxy-1-cyclopentene 
• 773837-37-9 sodium cyanide 

Downstream Products

• 194534-83-3 3-hydroxycyclopentane-carbonitrile 
• 24056-33-5 3-hydroxycyclohexanecarbonitrile 
• 159329-38-1 3,3-ethylenedioxycyclopentanecarbonitrile 
• 194534-84-4 3-cyanocyclopentyl 4-methylbenzenesulfonate 
• 13012-38-9 (1R)-3-oxocyclopentane-1-carboxylic acid 
• 71830-06-3 (-)-(S)-3-oxocyclopentanecarboxylic acid 
• 98-78-2 3-Oxo-cyclopentanecarboxylic acid 

Relevant articles and documents

Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst

A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.

D3 RECEPTOR AGONIST COMPOUNDS; METHODS OF PREPARATION; INTERMEDIATES THEREOF; AND METHODS OF USE THEREOF

Disclosed herein are novel compounds including dopamine D3 receptor agonists, compositions thereof, methods of use thereof, and processes of synthesizing the same. Further disclosed are D3R selective agonist compounds, specifically bitopic ligands comprising chirality.

Preparation of chiral 3-oxocycloalkanecarbonitrile and its derivatives by crystallization-induced diastereomer transformation of ketals with chiral 1,2-diphenylethane-1,2-diol

Chiral 3-oxocycloalkanecarbonitriles were prepared by fractional crystallization and crystallization-induced diastereomer transformation (CIDT) of diastereomeric ketals with (1R,2R)-1,2-diphenylethane-1,2-diol. Investigation of the crystal structures by X