374-14-1 Usage
Uses
2,2,3,3,3-Pentafluoropropylamine is used to prepare fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 374-14-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 374-14:
(5*3)+(4*7)+(3*4)+(2*1)+(1*4)=61
61 % 10 = 1
So 374-14-1 is a valid CAS Registry Number.
InChI:InChI=1/C3H4F5N.ClH/c4-2(5,1-9)3(6,7)8;/h1,9H2;1H
374-14-1Relevant articles and documents
Biomimetic reductive amination of perfluoroalkylcarboxylic acids to α,α-dihydroperfluoroalkylamines
Soloshonok, Vadim A,Ohkura, Hironari,Uneyama, Kenji
, p. 5449 - 5452 (2002)
The first general method for the reducing reagent-free, biomimetic transformation of perfluorocarboxylic acids to the α,α-dihydroperfluoroalkyl amines is reported. High chemical yields and simplicity of the experimental procedure render this method immediately useful and synthetically superior to the conventional approaches relying on application of reducing reagents.
