374067-83-1

Basic information

• Product Name: 4-[4-(4-bromo-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile
• Synonyms: 4-[4-(4-bromo-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile
• CAS NO: 374067-83-1
• Molecular Weight: 411.325
• Mol File: 374067-83-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[4-(4-bromo-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(4-bromo-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile(374067-83-1)
• EPA Substance Registry System: 4-[4-(4-bromo-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile(374067-83-1)

Safety Data

• Hazardous Substances Data: 374067-83-1(Hazardous Substances Data)

Upstream product

• 189956-45-4 4-[(4-hydroxy-2-pyrimidinyl)amino]benzonitrile 
• 89981-04-4 4-bromo-2,6-dimethylbenzenethiol 
• 244768-32-9 4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 943827-03-0 4-[2-(4-cyanophenylamino)pyrimidin-4-ylsulfanyl]-3,5-dimethylbenzoic acid ethyl ester 
• 943827-04-1 4-[4-(4-formyl-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benznitrile 
• 500293-65-2 4-[4-(4-hydroxymethyl-2,6-dimethylphenylsulfanyl)pyrimidin-2-ylamino]benzonitrile 

Relevant articles and documents

Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains

Novel diarylpyrimidines (DAPY), which represent next generation of non-nucleoside reverse transcriptase inhibitors (NNRTIs), were synthesized and their activities against human immunodeficiency virus type I (HIV-1) assessed. Modulations at positions 2 and