374077-57-3Relevant academic research and scientific papers
Novel use of a selenoalkyne within untraditionally mild D?tz benzannulation processes; total synthesis of a Calceolaria andina L. natural hydroxylated naphthoquinone
Caldwell,Colman,Kerr,Magennis
, p. 1428 - 1430 (2007/10/03)
A total synthesis of the Calceolaria andina L. extract 2-(1,1-dimethyl-2-propenyl)-3-hydroxy-1,4-naphthalenedione is described incorporating the first reported D?tz benzannulation of a selenoalkyne. Importantly, it has been shown that it is possible to effect this annulation at ambient temperature under dry state conditions with a significant improvement in cyclisation yield.
