3742-63-0

Basic information

• Product Name: Acetic acid isopropylidene-hydrazide
• Synonyms: Acetic acid isopropylidene-hydrazide;Acetone acetylhydrazone;N-(propan-2-ylideneamino)acetamide
• CAS NO: 3742-63-0
• Molecular Formula: C₅H₁₀N₂O
• Molecular Weight: 114.1457
• Mol File: 3742-63-0.mol

Chemical Properties

• Melting Point: 139.5-140 °C
• Boiling Point: 135-140 °C(Press: 7 Torr)
• Appearance: /
• Density: 0.97 g/cm³
• PKA: 14.54±0.46(Predicted)
• CAS DataBase Reference: Acetic acid isopropylidene-hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid isopropylidene-hydrazide(3742-63-0)
• EPA Substance Registry System: Acetic acid isopropylidene-hydrazide(3742-63-0)

Safety Data

• Hazardous Substances Data: 3742-63-0(Hazardous Substances Data)

Usage

Uses

Used in Corrosion Inhibition:
Acetic acid isopropylidene-hydrazide is used as a corrosion inhibitor for its ability to form complexes with metal ions, providing protection against corrosion in various industrial applications.
Used in Pharmaceutical Production:
AIIH is used as an intermediate in the production of pharmaceuticals due to its reactivity and ability to form complexes with metal ions, contributing to the development of new drugs.
Used in Agrochemical Production:
Acetic acid isopropylidene-hydrazide is utilized in the production of agrochemicals, where its complexing ability with metal ions can enhance the effectiveness of these products in agricultural applications.
Used in Disinfectants and Antibacterial Products:
AIIH is used as an active ingredient in disinfectants and antibacterial products due to its antimicrobial properties, helping to eliminate harmful microorganisms and maintain cleanliness and hygiene.

Upstream product

• 32085-24-8 2-acetyl-5-methyl-1,2,3-diazaphosphole 
• 141-43-5 ethanolamine 
• 120-80-9 benzene-1,2-diol 
• 121-44-8 triethylamine 
• 1068-57-1 acetic acid hydrazide 
• 67-64-1 acetone 

Downstream Products

• 1282516-77-1 2-(2-(4-bromo-2-fluorophenyl)-4-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-1H-imidazol-1-yl)ethanol 
• 1282516-76-0 5-(2-(4-bromo-2-fluorophenyl)-1H-imidazol-4-yl)-1-isopropyl-3-methyl-1H-1,2,4-triazole 
• 1282517-47-8 2-isopropyl-5-methyl-2H-[1,2,4]triazole-3-carboxylic acid ethyl ester 
• 1282517-46-7 2-bromo-1-(2-isopropyl-5-methyl-2H-[1,2,4]triazol-3-yl)-ethanone 
• 63751-70-2 2-acetyl-5-methyl-6,6-diphenyl-1-phospha-2,3-diazabicyclo-<3.1.0>hex-3-ene 
• 4466-50-6 1-acetyl-2-isopropylhydrazine 

Relevant articles and documents

Reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with butane-2,3-diol

The reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with (rac)-butane-2,3-diol at temperatures below 0 °C leads to the formation of a hydrospirophosphorane containing both a diazaphospholene and a dioxaphospholane ring system and a β-hydroxy-alkoxy-1,2,3-diazaphospholene. On heating, these products form a hydrospirotetraoxaphosphorane, its tautomeric monocyclic β-hydroxyalkylphosphite and N-acetyl-N'-isopropylidene-hydrazine.

BENZOXAZEPIN COMPOUNDS SELECTIVE FOR PI3K P110 DELTA AND METHODS OF USE

Benzoxazepin Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Catalytic hydrophosphorylation of alkyl- and acylhydrazones

N-Boc- and N-acylhydrazino phosphonates were obtained for the first time by hydrophos- phorylation of the appropriate hydrazones of aliphatic and aromatic aldehydes and heterocyclic and aliphatic ketones in the presence of [tetra(tert-butyl)phthalocyanine

1-Acyl-2-alkylhydrazines by the Reduction of Acylhydrazones

1-Acyl-2-alkylhydrazines were easily prepared by the reduction of acylhydrazones with triethylsilane in the presence of trifluoroacetic acid.

Reaction of carbonyl ylides with chloroform

Carbonyl ylides 2, generated by thermolysis of alkoxyoxadiazolines 1 in chloroform, react with chloroform to form ketals (3) of 1,1,1-trichloropropanone.The isotope effect at 80 deg C, determined by analysis of products from thermolysis of 1 in mixed solvent (CHCl3/CDCl3, both in large excess) was estimated to be kH/kD = 5.A mechanism involving concerted C-Cl and C-H bond formation between the ylide C atoms and the Cl and H atoms of chloroform is proposed.The ketals of 1,1,1-trichloropropanone are the first to be reported. Key words: carbonyl ylide, reaction with chloroform; chloroform, reaction with carbonyl ylides; ketals, of 1,1,1-trichloropropanone; 1,1,1-trichloropropanone, ketals of

THE REACTIONS OF 1,2,3-DIAZAPHOSPHOLE DERIVATIVES WITH CATECHOL

Both two-coordinated phosphorus compounds (1) and tri-coordinated phosphorus compounds (2) reacted with catechol in the presence of triethylamine to yield hexa-coordinated phosphorus compound R3P-H+N(Et)3 (3, R = -O-C6H4-O-). 3 were confirmed by elemental analysis, IR, 31P NMR and MS.The mechanism of these reactions was suggested.

Photolysis of 2-Alkoxy-Δ3-1,3,4-oxadiazolines. A New Route to Diazoalkanes

2-Alkoxy-2,5,5-trialkyl-Δ3-1,3,4-oxadiazolines (2), when photolyzed in solution with 300-nm light, afford the appropriate diazoalkane (3) and ester (4) in high yield.The diazoalkanes undergo intermolecular reaction, giving rise to azines (5), or they can be trapped in situ with 1,3-dipolarophiles to afford cycloadducts (7 or 11), which can in turn be photolyzed to the corresponding cyclopropenes (8) and cyclopropanes (12), respectively.

CONFORMATIONAL BEHAVIOUR AND E/Z ISOMERIZATION OF N-ACYL AND N-AROYLHYDRAZONES

The stereochemical behaviour of N-acyl and N-aroylhydrazones of aromatic aldehydes, of pyruvates and of acetone, in polar and less polar solvents, has been studied by HPLC and by NMR techniques.Z/E Geometrical isomers and cis/trans amide conformers have been found for N-acylhydrazones, while for N-aroylhydrazones only geometrical isomers were detected.Energy barriers of isomers are reported, and solvent effects are discussed with regard to hydrogen bond interactions.