3743-07-5 Usage
Uses
Used in Pharmaceutical Industry:
DIMETHYLCHLOROPHOSPHITE is used as a reagent for the synthesis of 2-alkyl-3-phosphonopropanoic acid derivatives, which are important intermediates in the development of antiviral and antibacterial drugs. These derivatives have shown potential in inhibiting viral replication and bacterial growth, making them valuable in the treatment of various infectious diseases.
Used in Biochemical Research:
DIMETHYLCHLOROPHOSPHITE is used in the preparation of pyrimidine nucleoside phosphonic acids, which are key compounds in the inhibition of human thymidine. These compounds have potential applications in the study of DNA synthesis and repair mechanisms, as well as in the development of novel antiviral and anticancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 3743-07-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,4 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3743-07:
(6*3)+(5*7)+(4*4)+(3*3)+(2*0)+(1*7)=85
85 % 10 = 5
So 3743-07-5 is a valid CAS Registry Number.
InChI:InChI=1/C2H6ClO2P/c1-4-6(3)5-2/h1-2H3
3743-07-5Relevant academic research and scientific papers
THE PREPARATION OF DIMETHYL PHOSPHOROCHLORIDITE AND ITS HOMOLOGS FROM TRIALKYL PHOSPHITES AND DICHLOROTRIPHENYLPHOSPHORANE
Majewski, Piotr
, p. 37 - 40 (2007/10/02)
A novel convenient sythesis of dialkyl phosphorochloridites based on the reaction of trialkyl phosphites with dichlorotriphenylphosphorane has been described.In this way the commomly used dialkyl phosphorochloridites (3a-e) were prepared in satisfactory yields.Their identity was confirmed by 31P-NMR spectroscopy as well as by their refractive index.
