3743-12-2

Upstream product

• 92044-52-5 1-(benzyloxy)-4-chloro-2-nitrobenzene 
• 74993-59-2 N-(3-Chloro-phenoxy)-benzamide 
• 74993-54-7 O-(m-chloro-phenyl)-hydroxylamine 
• 98-88-4 benzoyl chloride 
• 28443-50-7 2-amino-5-chlorophenol 
• 93-97-0 benzoic acid anhydride 
• 2866-82-2 N-(4-chlorophenyl)benzamide 

Downstream Products

• 877858-36-1 (8-chloro-3,4-dihydrobenzo[b][1,4]oxazepin-5(2H)-yl)(phenyl)methanone 
• 15952-20-2 6-chloro-2-phenylbenzo[d]oxazole 

Relevant academic research and scientific papers

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of Formula (0), Formula (I), and Formula (II) and methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein.

A diversity-oriented synthesis of bioactive benzanilides via a regioselective C(sp2)-H hydroxylation strategy

A diversity-oriented synthesis of bioactive benzanilides via C(sp2)-H hydroxylation has been studied. Different regioselectivity was observed with Ru(ii) and Pd(ii) catalysts. The reaction demonstrates excellent regioselectivity, good tolerance

Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases

Lipoxygenases catalyze the oxidation of unsaturated fatty acids, such as linoleic acid, which play a crucial role in inflammatory responses. Selective inhibitors may provide a new therapeutic approach for inflammatory diseases. In this study, we describe

VASOPRESSIN V1A ANTAGONISTS

The present invention concerns compounds inter alia according to general formula 1a. Compounds according to the invention are vasopressin V 1a receptor antagonists. Pharmaceutical compositions of the compounds are useful as treatment of dysmenorrhoea.

AlCl3-mediated migration of benzamido group of N-phenoxybenzamide derivatives to the phenyl group

AlCl3-mediated decomposition of N-phenoxybenzamide derivatives in dichloromethane mainly leads to regioselective intramolecular migration of benzamido group from the oxygen to the ortho position of the phenyl group via electron-deficient nitrogen intermediates.

Photolysis of 2-Nitrophenyl Benzyl Ethers in Neutral and Acidic Media

2-Nitrophenyl benzyl ethers (1a-d) on irradiation afford N-benzoyl-2-aminophenols (4) as the major products.The other minor products are 2-nitrophenol (2), 4-benzyl-2-nitrophenol (3), 2-phenylbenzoxazoles (5) and 2-nitrophenyl benzoate (6).A plausible mechanism to account for the formation of various products is discussed.