3743-23-5

Usage

Uses

Used in Dye Production:
5-Chloro-2-methoxyphenol is utilized as an intermediate in the synthesis of dyes, contributing to the coloration of textiles and other materials.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 5-chloro-2-methoxyphenol serves as a key component in the development of various medications, leveraging its chemical properties to enhance drug efficacy and formulation.
Used in Pesticide Formulation:
5-Chloro-2-methoxyphenol is employed as an active ingredient in pesticides, capitalizing on its antimicrobial properties to protect crops and control pests.
Used in Personal Care Products:
5-chloro-2-methoxy-phenol is used as a preservative in personal care products due to its antifungal and antimicrobial properties, ensuring the safety and longevity of these products.
Used in Cleaning Products:
5-Chloro-2-methoxyphenol is incorporated into cleaning products to provide effective antimicrobial action, helping to sanitize surfaces and maintain hygiene.
It is crucial to handle 5-chloro-2-methoxyphenol with care due to its moderate toxicity if ingested or absorbed through the skin, adhering to safety guidelines to ensure safe usage in all applications.

InChI:InChI=1/C7H7ClO2/c1-10-7-3-2-5(8)4-6(7)9/h2-4,9H,1H3

Upstream product

• 507-40-4 tert-butylhypochlorite 
• 90-05-1 2-methoxy-phenol 
• 95-03-4 5-chloro-2-methoxyaniline 
• 623-12-1 4-chloromethoxybenzene 
• 7035-09-8 5-chloro-2-methoxybenzaldehyde 
• 89694-48-4 5-chloro-2-methoxyphenyl boronic acid 
• 58735-58-3 2-(bromomethyl)-4-chloro-1-methoxybenzene 
• 56-23-5 tetrachloromethane 
• 636-93-1 5-nitroguaiacol 

Downstream Products

• 56913-09-8 (5-chloro-2-methoxy-phenoxy)-acetic acid 
• 879-98-1 guaiacol-5-sulfonic acid 
• 66037-03-4 2-acetoxy-4-chloro-1-methoxybenzene 
• 860686-92-6 2-allyloxy-4-chloro-1-methoxy-benzene 
• 88304-30-7 2-(2-Methoxy-5-chlorophenoxy)-3-<2-(N-formamido)ethyl>-2-cyclohexen-1-one 
• 256431-59-1 1-methoxy-2-methoxymethoxy-4-chlorobenzene 
• 721453-56-1 (+/-)-2-[(5-chloro-2-methoxyphenoxy)methyl]morpholine 
• 895572-26-6 3-chloro-5-(4-chloro-2-hydroxyphenoxy)benzonitrile 

Relevant academic research and scientific papers

COMPOUNDS FOR USE AS RADIOLIGANDS

The present invention relates to compounds, in particular those of formula (I) and formula (II) described herein, or pharmaceutically acceptable salts or solvates thereof, which may be used as radioligands in in vitro, ex vivo and in vivo beta cell imagin

Direct oxidation of the C(sp2)-C(sp3) bond from benzyltrimethylsilanes to phenols

A novel pathway for direct conversion of benzylsilanes to phenols by oxidation with Na2S2O8 and oxygen is efficiently developed under mild and neutral conditions. The reaction shows good functional group tolerance to afford phenols in moderate yields. The possible mechanism is proposed based on the isotopic labeling trials.

Combined Directed ortho Metalation/Suzuki-Miyaura cross-coupling strategies. Regiospecific synthesis of chlorodihydroxybiphenyls and polychlorinated biphenyls

(Chemical Equation Presented) The Directed ortho Metalation (DoM)/Suzuki-Miyaura cross-coupling strategy is applied for the regiospecific construction of all isomeric monochloro and selected dichloro and trichloro 2,3-dihydroxybiphenyls (DHBs). The combined methodology highlights iterative DoM processes, hindered Suzuki-Miyaura couplings, and advantages in diversity in approaches from commercial starting materials leading to provision of chloro-DHBs as single isomers in high purity and on a gram scale. The syntheis of several PCBs are also reported.

CHEMICAL COMPOUNDS

This invention relates to biaryl ether derivatives of formula (I), wherein R1, R3, R4, X, W, Y and m are defined in the description, and to compositions containing them and the uses of such derivatives. The compounds of th

Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine D4 receptor antagonists

The present invention relates to compounds of formula (I), any of it enantiomers, or any mixture thereof, or a pharmaceutically acceptable acid addition salt thereof, wherein R1, R2, R3, R4, R11, R12, R13, R14and R15each independently are hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, nitro, cyano, amino, acyl, alkylamino, dialkylamino, aminocarbonyl, or acylamino; R5 is hydrogen, alkyl, alkoxyalkyl, or phenylalkyl; X is —CH2—Z—, Z—CH2—, NH—CO—, —CO—NH—, or —CH═CH—; wherein Z is O, S, CH2, or NH; Y is O, —CH2—W—, —W—CH2—; wherein W is O, or S; and n is 0, 1 or 2. The compounds are useful in the treatment of psychotic disorders.

Directed ortho metalation and Suzuki-Miyaura cross-coupling connections: Regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs

Monochloro DHBs 1a-d and 2a-c have been regioselectively synthesised in good overall yields by a combination of directed ortho metalation and Suzuki- Miyaura cross-coupling.

APPLICATION OF LINEAR FREE ENERGY RELATIONSHIPS (LFER) IN THE AROMATIC HYDROXYLATION OF ANISOPLES BY CHROMIC ACID IN ACETIC ACID - WATER MIXTURES

Kinetics and mechanism of aromatic hydroxylation of anisoles by chromic acid has been investigated in 50percent aqueous acetic acid.The reaction followed secod order kinetics, first order each in and at constant and ionic strength.The effect of meta and para substituents on the reaction rates has been studied.The application of LFER to the rates reveals that the site of attack is at the ortho carbon atom but not at the oxygen atom.