374561-07-6

Basic information

• Product Name: 5-[4-chloro-3-(trifluoromethyl)phenyl]-1-phenyl-3a,6a-dihydrosprio[1H-furo[3,4-c]pyrrole-3,2'-(1'H)-indene]-1',3',4,6(2'H,3H,5H)-tetrone
• Synonyms: 5-[4-chloro-3-(trifluoromethyl)phenyl]-1-phenyl-3a,6a-dihydrosprio[1H-furo[3,4-c]pyrrole-3,2'-(1'H)-indene]-1',3',4,6(2'H,3H,5H)-tetrone
• CAS NO: 374561-07-6
• Molecular Formula: C27H15ClF3NO5
• Molecular Weight: 525.8599096
• Mol File: 374561-07-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[4-chloro-3-(trifluoromethyl)phenyl]-1-phenyl-3a,6a-dihydrosprio[1H-furo[3,4-c]pyrrole-3,2'-(1'H)-indene]-1',3',4,6(2'H,3H,5H)-tetrone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-chloro-3-(trifluoromethyl)phenyl]-1-phenyl-3a,6a-dihydrosprio[1H-furo[3,4-c]pyrrole-3,2'-(1'H)-indene]-1',3',4,6(2'H,3H,5H)-tetrone(374561-07-6)
• EPA Substance Registry System: 5-[4-chloro-3-(trifluoromethyl)phenyl]-1-phenyl-3a,6a-dihydrosprio[1H-furo[3,4-c]pyrrole-3,2'-(1'H)-indene]-1',3',4,6(2'H,3H,5H)-tetrone(374561-07-6)

Safety Data

• Hazardous Substances Data: 374561-07-6(Hazardous Substances Data)

Upstream product

• 5381-33-9 2-benzylidene-indan-1,3-dione 
• 54647-10-8 N-(4'-Chlor-3'-trifluormethyphenyl)-maleinimid 
• 43053-57-2 3-phenylspirocyclic [oxirane-2,2'-indan]-1',3'-dione 

Relevant articles and documents

A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases

We have identified a series of spirocyclic furan and pyrrolidine inhibitors of Enterococeus faecalis and Staphylococcus aureus phenylalanyl-tRNA synthetases. The most potent analogue 1b showed IC50=5 nM (E. faecalis PheRS) and IC50=2