43053-57-2

Basic information

• Product Name: Spiro[2H-indene-2,2'-oxirane]-1,3-dione, 3'-phenyl-
• Synonyms: 3-Phenylspiro-1',3'-dion;
• CAS NO: 43053-57-2
• Molecular Formula: C16H10O3
• Molecular Weight: 250.254
• Mol File: 43053-57-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Spiro[2H-indene-2,2'-oxirane]-1,3-dione, 3'-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[2H-indene-2,2'-oxirane]-1,3-dione, 3'-phenyl-(43053-57-2)
• EPA Substance Registry System: Spiro[2H-indene-2,2'-oxirane]-1,3-dione, 3'-phenyl-(43053-57-2)

Safety Data

• Hazardous Substances Data: 43053-57-2(Hazardous Substances Data)

Upstream product

• 5381-33-9 2-benzylidene-indan-1,3-dione 

Downstream Products

• 127322-78-5 exo-4-oxa-3-phenyl-5,5-phthaloyltricyclo<5.2.1.0^2,6>decane 
• 5508-42-9 2-dimethylsulfuranylideneindane-1,3-dione 
• 91403-94-0 2-phenyl-3,3,4,4-diphthaloyloxetane 
• 100-52-7 benzaldehyde 
• 127322-81-0 4-oxa-5-phenyl-3,3-phthaloyl-10,11-benzotricyclo<5.2.2.0^2,6>undec-8(9)-ene 
• 120393-35-3 4-nitro-2-phthaloyl-3,5-diphenyltetrahydrofuran 
• 127322-83-2 12,13-dimethoxycarbonyl-5-oxa-4-phenyl-6,6-phthaloyltetracyclo<7.2.2.0^2,80^3,7>tridec-10-ene 
• 1150-59-0 2-hydroxy-3-phenyl-1,4-naphthoquinone 
• 374561-07-6 C₂₇H₁₅ClF₃NO₅ 
• 262847-97-2 C₂₇H₁₈ClNO₅ 
• 262847-97-2 C₂₇H₁₈ClNO₅ 
• 127322-82-1 exo-4-oxa-3-phenyl-5,5-phthaloyltricyclo<5.2.1.0^2,6>dec-8-ene 
• 120393-37-5 2-phthaloyl-5-phenyltetrahydrofuran-3,4-dicarboxylic acid anhydride 

Relevant articles and documents

Asymmetric Epoxidation of Enones Promoted by Dinuclear Magnesium Catalyst

Asymmetric synthesis with cheaper and non-toxic alkaline earth metal catalysts is becoming an important and sustainable alternative to conventional catalytic methodologies mostly relying on precious metals. In spite of some sustainable methods for enantioselective epoxidation of enones, the development of a well-defined and efficient catalyst based on magnesium complexes for these reactions is still a challenging task. In this perspective, we present the application of chiral dinuclear magnesium complexes for asymmetric epoxidation of a broad range of electron-deficient enones. We demonstrate that the in situ generated magnesium-ProPhenol complex affords enantioenriched oxiranes in high yields and with excellent enantioselectivities (up to 99% ee). Our extensive study verifies the literature data in this area and provides a step forward to better understand the factors controlling the oxygenation process. Elaborated catalyst offers mild reaction conditions and a truly wide substrate scope. (Figure presented.).

A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases

We have identified a series of spirocyclic furan and pyrrolidine inhibitors of Enterococeus faecalis and Staphylococcus aureus phenylalanyl-tRNA synthetases. The most potent analogue 1b showed IC50=5 nM (E. faecalis PheRS) and IC50=2

Heterocycles as antimicrobial agents

Methods for treating infection and related compositions, compounds of formula I as defined in the application and methods for preparing same, are provided. In general, the compounds inhibit transfer ribonucleic acid (tRNA) synthetase and are useful as ant