37464-87-2

Upstream product

• 13159-16-5 5-phenyl-4-penten-1-ol 
• 7333-63-3 4-bromobutylphosphonium bromide 
• 100-52-7 benzaldehyde 
• 110-52-1 1,4-dibromo-butane 
• 37464-84-9 methyl 5-acetoxy-5-phenylpentanoate 
• 37464-85-0 methyl 5-phenylpent-4-enoate 
• 91142-54-0 2-phenylcyclobutanecarboxylic acid 

Downstream Products

• 158478-40-1 (E)-N-allyl-5-phenylpent-4-en-1-amine 
• 247118-17-8 (Z)-N,N-diethyl-5-phenylpent-4-enylamine 
• 1030020-55-3 5-phenyl-4-penten-1-nitrate 
• 1330074-79-7 C₁₆H₁₆ClNO 
• 1330074-86-6 3-chloro-2-(5-phenylpent-4-enyl)isoquinolin-1(2H)-one 
• 1352632-13-3 C₂₀H₁₈INO 
• 1352632-11-1 C₂₀H₁₈ClNO 
• 1226985-27-8 (E)-dimethyl 5-phenylpent-4-enylphosphonate 
• 144220-38-2 trans-N-allyl-N-(benzenesulfenyl)-5-phenylpent-4-enylamine 
• 99896-08-9 8-phenylindolizidine 
• 247118-16-7 (E)-N,N-diethyl-5-phenylpent-4-enylamine 
• 244235-63-0 2,7-diphenyl-2-(methylseleno)heptene 

Relevant academic research and scientific papers

One-pot synthesis of fused benzo[c]carbazoles by photochemical intramolecular annulation of 3-acyl-2-haloindoles with tethered styrenes

An efficient procedure for the synthesis of fused benzo[c]carbazoles has been achieved in moderate to high yields by the one-pot photochemical annulation of 3-acyl-2-haloindoles with tethered styrenes by photoinduced electron-transfer coupling, electrocyclic reactions, and deacylative aromatization in the presence of pyridine. Fused furo[2,3-c]carbazoles were also synthesized under the same conditions. 5,6-Dihydrobenzo[c]pyrrolo[1,2,3-lm] carbazoles were oxidized by DDQ to afford aromatic benzo[c]pyrrolo[1,2,3-lm] carbazole products in moderate to high yields.

One-pot synthesis of benzo[f]quinolin-3-ones and benzo[a]phenanthridein-5- ones by the photoanuulation of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1- ones to phenylacetylene

The one-pot synthesis of benzo[f]quinolin-3-ones and benzo[a] phenanthridein-5-ones was achieved by the inter- and intramolecular photoannulation of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1-ones with phenylacetylene or tethered phenylacetylene. The reactions were proceeded by photoaddition of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1-ones to phenylacetylene to give the chlorine-substituted stilbenoids, and then 6π electrocyclization of the stilbenoids and oxidation aromatization to afford the polycyclic products.

Nitrite anion: The key intermediate in alkyl nitrates degradative mechanism

Alkyl nitrates are metabolized in vitro to yield nitric oxide, and thiol groups have long been considered necessary cofactors. Here, we report evidence that no reaction between thiols and alkyl nitrates takes place in vitro, but stronger reducing agents, such as iron(II) derivatives, are necessary; alkoxy radicals and nitrite anions are the reaction intermediates. The latter, in slightly acidic conditions, can nitrosate thiols to the corresponding S-nitrosothiols, the real NO releasers.

Synthesis of pyrrolizidines using aminyl radicals generated from sulfenamide precursors

Tandem radical cyclisations of aminyl radicals generated from sulfenamide precursors have been used for the synthesis of pyrrolizidines and other polycyclic nitrogen heterocycles. The aminyl radicals are generated by reaction between sulfenamide precursor

FORMATION AND REARRANGEMENT OF THE GRIGNARD REAGENT FROM 2-PHENYLCYCLOBUTYLMETHYL BROMIDE

Reaction of cis- or trans-2-phenylcyclobutylmethyl bromide with magnesium produces the rearranged 5-phenyl-1-penten-5-ylmagnesium compound 7 in addition to the unrearranged Grignard reagent 6.The former appears to result from very rapid rearrangement of a radical intermediate in the process of Grignard reagent formation.Rearrangement of 6 to 7 also occurs, at a rate which is accelerated by the phenyl group.