374695-15-5Relevant articles and documents
Synthesis and in vitro antibacterial and antifungal activities of benzoxazole derivatives
Khan, Khalid Mohammed,Karim, Aneela,Ambreen, Nida,Amyn, Afroz,Saied, Sumayya,Ahmed, Aqeel,Perveen, Shahnaz
, p. 894 - 900 (2013/07/26)
The in vitro antibacterial and antifungal activities of twenty-nine (29) benzoxazole derivatives were tested against fifteen Gram-positive and sixteen Gram-negative strains. Out of the twenty-nine compounds, eighteen compounds 3-5, 7-9, 11-13, 15-25 showed a broad range of activity against tested Gram-positive microorganisms, whereas rest of the compounds 6, 10, 14 and 26-31 were found to be completely inactive against all the tested strains of Gram-positive bacteria. Five compounds 8, 11-13, and 15 showed activities against Gram-negative strains whereas the rest were devoid of any activity. Twenty-one (21) out of twenty-nine (29) compounds possessed antifungal activity. The structures of the synthetic compounds were confirmed by IR, EIMS and 1HNMR spectral data.