37471-70-8

Basic information

• Product Name: 2-Propen-1-one, 1-(4-ethylphenyl)-3-phenyl-
• CAS NO: 37471-70-8
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• Mol File: 37471-70-8.mol

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(4-ethylphenyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(4-ethylphenyl)-3-phenyl-(37471-70-8)
• EPA Substance Registry System: 2-Propen-1-one, 1-(4-ethylphenyl)-3-phenyl-(37471-70-8)

Safety Data

• Hazardous Substances Data: 37471-70-8(Hazardous Substances Data)

Upstream product

• 937-30-4 4-ethylacetophenone 
• 100-51-6 benzyl alcohol 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 25309-64-2 4-ethyl-1-iodobenzene 
• 100-52-7 benzaldehyde 

Downstream Products

• 95437-37-9 1-(4-ethyl-phenyl)-3-anilino-3-phenyl-propan-1-one 
• 1334222-43-3 3-(4-ethylphenyl)-1-methyl-5-phenyl-4,5-dihydro-1H-pyrazole 
• 1342310-57-9 4-(4-ethylphenyl)-6-phenyl-5,6-dihydropyrimidin-2(1H)-one 
• 1247902-11-9 3-cyano-2-(1H-indol-3-yl)-4-phenyl-6-(4-ethylphenyl)pyridine 
• 43008-74-8 1-(4-ethylphenyl)-3-phenylpropane-1-one 

Relevant articles and documents

Iridium and copper supported on silicon dioxide as chemoselective catalysts for dehydrogenation and borrowing hydrogen reactions

High active ligand usually plays an important role during catalysis and synthesis chemistry. A new and efficient benzotriazole-pyridinyl-silane ligand (BPS) was designed, and the corresponding iridium and copper catalysts were synthesized and thoroughly characterized by means of EDS, TEM, and XPS. The resulting iridium composite revealed excellent catalytic activity for the reaction of tert-butanesulfinamide with benzyl alcohols, while copper catalyst could realize the synthesis of unsaturated carbonyl compounds through the reaction of benzyl alcohols with ketones. This provided an efficient method for selective synthesis of unsaturated carbonyl compounds from benzyl alcohols and ketones in high yields with good recovery performance.

Method for ultraviolet illumination synthesis of chalcone compound

The present invention discloses a method for ultraviolet illumination synthesis of a chalcone compound. According to the method, g-C3N4 is adopted as a photocatalyst, a sodium salt adopted as an auxiliary catalyst is added or is not added, and one selected from benzaldehyde and a derivative thereof and one selected from acetophenone and a derivative thereof are adopted as reaction substrates under ultraviolet light irradiation to generate the chalcone compound. Compared to the traditional catalytic method, the method of the present invention has the following advantages that the solvent is not required, the reaction is rapid, the substrate has high universality, the conversion rate is high, the selectivity is good, and the like, wherein the conversion rates of acetophenone and the derivative are more than 90%, and the selectivity of chalcone is more than 95%.

A new solid acid catalyst FeCl3/bentonite for aldol condensation under solvent-free condition

For the first time, a new solid acid catalyst has been used for the synthesis of aryl chalcones under solvent free conditions. A simple method (solid dispersion method) has been adopted for the synthesis of FeCl3/bentonite. The prepared catalyst has been characterized by different characterization techniques. A series of E-1-(substituted phenyl)-3-(1-pyrenyl)-2-propen-1-ones have been synthesized using FeCl3/bentonite under microwave-assisted solvent-free conditions. The yields are in the range from 80 to 88%. All the synthesized chalcones have been characterized by their physical constants, analytical, IR, 1H and 13C NMR spectral data. This catalyst can be reused for further runs (after fifth cycle) without decrease in activity. This catalyst gives excellent yields and is inexpensive and easily recyclable for this reaction.

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.

A straightforward synthesis of pyrazolines and pyrazoles: Palladium-catalyzed carbonylative vinylation-cyclocondensation reactions of aryl halides

A novel consecutive one-pot synthesis of pyrazolines and pyrazoles starting from simple aryl halides, styrenes, carbon monoxide, and hydrazines has been established. Palladium-catalyzed carbonylative vinylation of aryl halides gave the corresponding chalcones, which are trapped in situ by addition of hydrazines.

Facile synthesis and characterization of substituted pyrimidin-2(1H)-ones and their chalcone precursors

A new and efficient method has been developed for the quantitative transformation of chalcones to pyrimidine frame work vSa solid support catalysis, Silica supported sulphuric acid (SSA) efficiently catalyzed the reaction of α-β-unsaturated earbonyl, chalcones (140) with urea to afford substituted pyriniidin-2(1H)-ones (11-20) hi good to excellent yield. The interesting behaviour of SSA lies in the thct that it can be re-used after simple washing with chloroform thereby rendering this procedure more economical, The chemical structures were confirmed by analytical data as well as spectroscopic means.

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.