374716-65-1

Basic information

• Product Name: 1-Propanol, 3-[(4-methoxyphenyl)methoxy]-2-methyl-, acetate, (2R)-
• CAS NO: 374716-65-1
• Molecular Formula: C14H20O4
• Molecular Weight: 252.31
• Mol File: 374716-65-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Propanol, 3-[(4-methoxyphenyl)methoxy]-2-methyl-, acetate, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanol, 3-[(4-methoxyphenyl)methoxy]-2-methyl-, acetate, (2R)-(374716-65-1)
• EPA Substance Registry System: 1-Propanol, 3-[(4-methoxyphenyl)methoxy]-2-methyl-, acetate, (2R)-(374716-65-1)

Safety Data

• Hazardous Substances Data: 374716-65-1(Hazardous Substances Data)

Upstream product

• 55289-53-7 1,3-diacetoxy-2-methylpropane 
• 2746-25-0 p-Methoxybenzyl bromide 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 119786-13-9 (2R)-acetic acid 3-hydroxy-2-methyl-propyl ester 
• 108-05-4 vinyl acetate 
• 374716-64-0 (+/-)-3-(4-methoxybenzyloxy)-2-methyl-1-propanol 

Downstream Products

• 1585968-88-2 1-{[(2R,3S)-3-(methoxymethoxy)-2-methylpent-4-enyloxy]methyl}-4-methoxybenzene 
• 1585968-87-1 (3R,4R)-5-(4-methoxybenzyloxy)-4-methylpent-1-en-3-ol 
• 1610458-36-0 (3S,4R)-5-(4-methoxybenzyloxy)-4-methylpent-1-en-3-ol 
• 1453867-93-0 (R)-5-((4-methoxybenzyl)oxy)-4-methylpent-1-en-3-one 
• 449174-20-3 methyl (R)-N-methyl-N-methoxy-3-(4-methoxybenzyloxy)-2-methylpropanoate 
• 640283-74-5 (R)-3-((4-methoxybenzyl)oxy)-2-methylpropanoic acid 
• 1585968-89-3 1-{[(2R,3R)-3-(methoxymethoxy)-2-methylpent-4-enyloxy]methyl}-4-methoxybenzene 
• 160238-46-0 (2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal 

Relevant articles and documents

Chemoenzymatic asymmetric total synthesis of nonanolide (Z)-cytospolides D, E and their stereoisomers

Chemoenzymatic asymmetric total synthesis of the (Z)-isomer of the naturally occurring decanolide cytospolides D, E and six stereoisomers is reported. The main highlight of the synthetic venture involves ring-closing metathesis (RCM) reaction of a suitably functionalized ester compound, which was assembled by the Yamaguchi coupling of the required acid and alcohol fragments. The alcohol fragment was ac- cessed by two alternative chemoenzymatic processes, one being hydroxynitrile lyase mediated hydrocyanation, whereas lipase-catalyzed transesterification was the key sep in the second route. The acid fragment was constructed by an enantioselective enzymatic desymmetrization (EED) of prochiral 2-methyl-1,3-propanediol and Corey-Bakshi-Shibata (CBS) mediated stereoselective carbonyl reduction.

Chemoenzymatic Approach toward the Pure Enantiomers of 2-Methyl-1,3-propanediol Mono(p-Methoxybenzyl Ether)

In a route towards the enantiomerically pure 2-methylpropane-1,3-diol mono(p-methoxybenzyl ether), which is an important starting material for natural product synthesis, a kinetic resolution approach by means of lipase-catalyzed hydrolysis as well as acyl