374803-65-3

Upstream product

• 374803-67-5 2-bromo-N,5-dimethoxy-N-methylbenzamide 
• 35450-36-3 methyl 2-bromo-5-methoxybenzoate 
• 60080-98-0 (2-bromo-5-methoxyphenyl)(phenyl)methanone 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 374803-72-2 (2-bromo-5-hydroxyphenyl)-(phenyl)methanone 

Downstream Products

• 374803-70-0 (2S)-2-[(2-benzoyl-4-{[2-(trimethylsilyl)ethoxy]methoxy}phenyl)amino]-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propanoic acid 
• 374803-66-4 (S)-2-[2-Benzoyl-4-(2-trimethylsilanyl-ethoxymethoxy)-phenylamino]-3-(4-benzyloxy-phenyl)-propionic acid 

Relevant academic research and scientific papers

The synthesis of GW710936X to support the development of potent PPARγ agonists

(2S)-[(2-Benzoyl-4-hydroxy-phenyl)amino]-3-{4-[2-(5-methyl-2-phenyloxazol-4- yl)ethoxy]phenyl}propanoic acid has been synthesised from N-Cbz-L-tyrosine methyl ester utilising a copper(I) catalysed N-arylation as the key coupling step. The synthetic route