60080-98-0

Basic information

• Product Name: 2-BROMO-5-METHOXYBENZOPHENONE
• Synonyms: 2-BROMO-5-METHOXYBENZOPHENONE;(2-Bromo-5-methoxyphenyl)(phenyl)methanone
• CAS NO: 60080-98-0
• Molecular Formula: C₁₄H₁₁BrO₂
• Molecular Weight: 291.14
• Mol File: 60080-98-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 42-44 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 396.3°C at 760 mmHg
• Flash Point: 193.5°C
• Appearance: /
• Density: 1.401g/cm³
• Vapor Pressure: 1.72E-06mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BROMO-5-METHOXYBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-METHOXYBENZOPHENONE(60080-98-0)
• EPA Substance Registry System: 2-BROMO-5-METHOXYBENZOPHENONE(60080-98-0)

Safety Data

• Hazardous Substances Data: 60080-98-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-methoxybenzophenone is a chemical compound that belongs to the benzophenone class of organic compounds. It is a brominated derivative of 5-methoxybenzophenone and is commonly used as a photoinitiator in the production of photopolymers and adhesives. 2-BROMO-5-METHOXYBENZOPHENONE has the ability to absorb ultraviolet (UV) radiation and undergo a photoreaction, which initiates the polymerization process. It is also used as a stabilizer in plastics and as an intermediate in the synthesis of various pharmaceuticals and other organic compounds. However, 2-bromo-5-methoxybenzophenone should be handled with caution as it is a potentially hazardous chemical with possible health and environmental risks.

InChI:InChI=1/C14H11BrO2/c1-17-11-7-8-13(15)12(9-11)14(16)10-5-3-2-4-6-10/h2-9H,1H3

Upstream product

• 100-59-4 phenylmagnesium chloride 
• 374803-67-5 2-bromo-N,5-dimethoxy-N-methylbenzamide 
• 71-43-2 benzene 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 60080-99-1 (2-bromo-5-methoxyphenyl)(phenyl)methanol 
• 7507-86-0 2-bromo-5-methoxy-benzaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 35450-36-3 methyl 2-bromo-5-methoxybenzoate 
• 56658-04-9 2-bromo-5-methoxybenzoyl chloride 

Downstream Products

• 913191-88-5 1-bromo-4-methoxy-2-(2-methoxy-1-phenylethenyl)benzene 
• 869301-30-4 2-benzoyl-4-methoxybenzonitrile 
• 1569316-10-4 (2-bromo-5-methoxyphenyl)(diphenyl)methanol 
• 1569315-97-4 1-(2-bromo-5-methoxyphenyl)-1-phenylethanol 
• 1569316-37-5 1-(2-bromo-5-methoxyphenyl)-1-phenylbut-3-en-1-ol 
• 1569316-32-0 1-(2-bromo-5-methoxyphenyl)-1-phenylprop-2-yn-1-ol 
• 1569315-52-1 3,8-dimethoxy-6-methyl-6-phenyl-6H-benzo[c]chromene 
• 98-86-2 acetophenone 
• 119-61-9 benzophenone 
• 1569315-66-7 3,8-dimethoxy-6,6-diphenyl-6H-benzo[c]chromene 
• 1569315-87-2 6-methoxy-3-methylene-1-phenylindan-1-ol 
• 1569315-89-4 6-methoxy-3-methyl-1-phenyl-1H-inden-1-ol 
• 1597428-48-2 2-iodo-5-methoxybenzophenone 
• 1597428-49-3 2-(3,3-dimethylbut-1-ynyl)-5-methoxybenzophenone 

Relevant articles and documents

The first formation of (1Z)-1-alkylidene-1H-isobenzofuranium amides and 1H-inden-1-ones: Acid-promoted 5-exo cyclization and hydration/aldol condensation reactions of o-ethynylbenzophenones

(1Z)-1-(2,2-Dimethylpropylidene)-1H-isobenzofuranium bis(trifluoromethylsulfonyl)amides were synthesized through 5-exo cyclization reactions between sterically encumbered o-alkynylbenzophenones and bis(trifluoromethylsulfonyl)imide (Tf2NH). It

Substitution controlled functionalization of ortho -bromobenzylic alcohols via palladium catalysis: Synthesis of chromenes and indenols

An efficient domino Pd-catalyzed transformation of simple ortho-bromobenzyl tertiary alcohols to chromenes is presented. Their formation is believed to proceed via the formation of a five-membered palladacycle, which, in turn, involves in an intermolecular homocoupling with the second ortho- bromobenzyltertiary alcohol to yield the homo-biaryl bond followed by intramolecular C-O bond formation. Interestingly, when there is an allylic substituent on the benzylic carbon atom, a chemoselective switch was observed, which preferred intramolecular Heck coupling and gave indenols. Further, it has been confirmed that the tertiary alcohol functionality is indispensible to give the coupled products, whereas the use of primary/secondary benzylic alcohols furnished the simple carbonyl products via a possible reductive debromination followed by oxidation due to the availability of β-hydrogen(s).

Synthesis of 3-substituted indazoles and benzoisoxazoles via Pd-catalyzed cyclization reactions: application to the synthesis of nigellicine

Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished with the aid of Pd-catalyzed intramolecular carbon-nitrogen and carbon-oxygen bond formations. The catalyst system described herein allows the cyclization to proceed under very mild conditions and thus could be applied to a wide range of substrates with acid- or base-sensitive functional groups. A total synthesis for the indazole ring-containing natural product nigellicine is also described.