374937-38-9

Basic information

• Product Name: but-2-ynyl-((R)-1-phenyl-ethyl)-amine
• Synonyms: but-2-ynyl-((R)-1-phenyl-ethyl)-amine
• CAS NO: 374937-38-9
• Molecular Weight: 173.258
• Mol File: 374937-38-9.mol

Chemical Properties

• CAS DataBase Reference: but-2-ynyl-((R)-1-phenyl-ethyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: but-2-ynyl-((R)-1-phenyl-ethyl)-amine(374937-38-9)
• EPA Substance Registry System: but-2-ynyl-((R)-1-phenyl-ethyl)-amine(374937-38-9)

Safety Data

• Hazardous Substances Data: 374937-38-9(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 61493-85-4 but-2-yn-1-yl methanesulfonate 

Downstream Products

• 845817-48-3 ({but-2-ynyl[(R)-1-phenylethyl]carbamoyl}methyl)carbamic acid tert-butyl ester 
• 845817-50-7 {(1S,2S)-2-methyl-1-[(R)-(1-phenylethyl)carbamoyl]but-3-enyl}carbamic acid benzyl ester 
• 845817-63-2 {[((Z)-But-2-enyl)-((R)-1-phenyl-ethyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 845817-49-4 2-amino-N-[(Z)-but-2-enyl]-N-[(R)-1-phenylethyl]acetamide 

Relevant articles and documents

Asymmetric total syntheses of marine cyclic depsipeptide halipeptins A-D

Halipeptins A-D (1a-d) are a family of natural cyclic depsipeptides isolated from marine sponges. Total syntheses of these four compounds are detailed in this report. The key elements in this synthesis include the elaboration of the polysubstituted decanoic acid parts by two asymmetric aldol reactions, assembly of the N-methyl-δ-hydroxyisoleucine residue by using either aza-Claisen rearrangement or methylation of aspartates as the key steps, and macrocyclization at the polysubstituted decanoic acid alanine site.

A convenient method for 3-pyrroline synthesis.

[reaction: see text]. The synthesis of a range of 3-pyrrolines has been achieved from primary amine starting materials using a two-step alkylation/alkylidene carbene CH-insertion reaction sequence. We have shown that insertion into a range of CH-bond type