845817-49-4

Basic information

• Product Name: Acetamide, 2-amino-N-(2Z)-2-butenyl-N-[(1R)-1-phenylethyl]-
• CAS NO: 845817-49-4
• Molecular Formula: C14H20N2O
• Molecular Weight: 232.326
• Mol File: 845817-49-4.mol

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-amino-N-(2Z)-2-butenyl-N-[(1R)-1-phenylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-amino-N-(2Z)-2-butenyl-N-[(1R)-1-phenylethyl]-(845817-49-4)
• EPA Substance Registry System: Acetamide, 2-amino-N-(2Z)-2-butenyl-N-[(1R)-1-phenylethyl]-(845817-49-4)

Safety Data

• Hazardous Substances Data: 845817-49-4(Hazardous Substances Data)

Upstream product

• 374937-38-9 but-2-ynyl-((R)-1-phenyl-ethyl)-amine 
• 845817-48-3 ({but-2-ynyl[(R)-1-phenylethyl]carbamoyl}methyl)carbamic acid tert-butyl ester 
• 845817-63-2 {[((Z)-But-2-enyl)-((R)-1-phenyl-ethyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester 

Downstream Products

• 845817-50-7 {(1S,2S)-2-methyl-1-[(R)-(1-phenylethyl)carbamoyl]but-3-enyl}carbamic acid benzyl ester 

Relevant articles and documents

Asymmetric total syntheses of marine cyclic depsipeptide halipeptins A-D

Halipeptins A-D (1a-d) are a family of natural cyclic depsipeptides isolated from marine sponges. Total syntheses of these four compounds are detailed in this report. The key elements in this synthesis include the elaboration of the polysubstituted decanoic acid parts by two asymmetric aldol reactions, assembly of the N-methyl-δ-hydroxyisoleucine residue by using either aza-Claisen rearrangement or methylation of aspartates as the key steps, and macrocyclization at the polysubstituted decanoic acid alanine site.