37496-85-8

Upstream product

• 37496-81-4 N'-(cyano-phenyl-methylene)-benzamidrazone 
• 116178-05-3 3,6-diphenyl-1,2,4-triazine-5-carbonitrile 
• 25131-36-6 N'-(cyano-phenyl-methylene)-benzohydrazonoyl chloride 
• 106474-32-2 4-nitroso-3,5-diphenyl-1H-pyrazole 
• 33859-69-7 3,6-diphenyl-1,2,4-triazine 4-oxide 

Downstream Products

• 36214-25-2 3,6-diphenyl-4H-[1,2,4]triazin-5-one 

Relevant academic research and scientific papers

Transformations of 1,2,4-triazines in reactions with nucleophiles: V. SNH and ipso-substitution in the synthesis and transformations of 5-cyano-1,2,4-triazines

The scope of functionalization of 1,2,4-triazines can be considerably extended via successive nucleophilic substitution of hydrogen (S NH) and ipso-substitution. A convenient procedure has been developed for direct cyanation of 1,2,4-triazine 4-oxides with acetone cyanohydrin in the presence of triethylamine. The cyano group in the resulting 5-cyano-1,2,4-triazines is readily replaced by reactions with various aliphatic alcohols and amines.