36214-25-2

Usage

Uses

Used in Pharmaceutical Industry:
3,6-DIPHENYL-1,2,4-TRIAZIN-5-OL is used as an active pharmaceutical ingredient for the development of new drugs and treatments. Its antimicrobial and antifungal properties make it a promising candidate for addressing various infections and diseases.
Used in Dye Industry:
3,6-DIPHENYL-1,2,4-TRIAZIN-5-OL is used as a key intermediate in the manufacturing of dyes, contributing to the production of a wide range of colorants used in various applications, including textiles, plastics, and printing inks.
Used in Organic Electronics:
Due to its unique electronic properties, 3,6-DIPHENYL-1,2,4-TRIAZIN-5-OL has potential applications in the field of organic electronics. It is the subject of ongoing research for its potential use in the development of electronic devices, such as organic light-emitting diodes (OLEDs) and organic solar cells.
Used in Antimicrobial and Antifungal Applications:
3,6-DIPHENYL-1,2,4-TRIAZIN-5-OL is used as an antimicrobial and antifungal agent, providing a natural alternative for the treatment of various infections caused by bacteria and fungi. Its effectiveness in inhibiting the growth of harmful microorganisms makes it a valuable component in the development of new treatments and preventive measures.

InChI:InChI=1/C15H11N3O/c19-15-13(11-7-3-1-4-8-11)17-18-14(16-15)12-9-5-2-6-10-12/h1-10H,(H,16,18,19)

Upstream product

• 41940-16-3 3,6-diphenyl-5-methyl-1,2,4-triazine 
• 37496-85-8 5-amino-3,6-diphenyl-1,2,4-triazine 
• 106474-32-2 4-nitroso-3,5-diphenyl-1H-pyrazole 
• 37496-81-4 N'-(cyano-phenyl-methylene)-benzamidrazone 
• 25131-36-6 N'-(cyano-phenyl-methylene)-benzohydrazonoyl chloride 
• 28819-30-9 benzamidrazone 
• 611-73-4 Benzoylformic acid 
• 116178-05-3 3,6-diphenyl-1,2,4-triazine-5-carbonitrile 
• 33859-69-7 3,6-diphenyl-1,2,4-triazine 4-oxide 
• 613-94-5 benzoic acid hydrazide 
• 57750-39-7 benzoyl cyanide azine 
• 80403-30-1 Benzoic acid [1-cyano-1-phenyl-meth-(Z)-ylidene]-hydrazide 
• 65961-93-5 Bromo-ethylsulfanyl-phenyl-acetonitrile 

Downstream Products

• 94398-27-3 5-chloro-3,6-diphenyl-as-triazine 
• 33063-35-3 3,6-diphenyl-[1,2,4]triazine 
• 110393-58-3 3,6-diphenyl-4H-[1,2,4]triazine-5-thione 
• 108718-69-0 (3,6-diphenyl-[1,2,4]triazin-5-yl)-hydrazine 
• 126542-66-3 3,6-Diphenyl-5-undec-10-ynyloxy-[1,2,4]triazine 
• 126542-63-0 5-Hex-5-ynyloxy-3,6-diphenyl-[1,2,4]triazine 
• 94398-29-5 C₁₈H₁₇N₃OS 
• 94398-23-9 3,6-Diphenyl-5-propyl-[1,2,4]triazine 
• 94398-22-8 5-ethyl-3,6-diphenyl-1,2,4-triazine 
• 41940-16-3 3,6-diphenyl-5-methyl-1,2,4-triazine 
• 54637-94-4 5-methoxy-3,6-diphenyl-1,2,4-triazine 
• 94398-41-1 5-phenacyl-3,6-diphenyl-1,2,4-triazine 
• 116178-05-3 3,6-diphenyl-1,2,4-triazine-5-carbonitrile 
• 116178-03-1 Cyano-(3,6-diphenyl-[1,2,4]triazin-5-yl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

Transformations of 1,2,4-triazines in reactions with nucleophiles: V. SNH and ipso-substitution in the synthesis and transformations of 5-cyano-1,2,4-triazines

The scope of functionalization of 1,2,4-triazines can be considerably extended via successive nucleophilic substitution of hydrogen (S NH) and ipso-substitution. A convenient procedure has been developed for direct cyanation of 1,2,4-triazine 4-oxides with acetone cyanohydrin in the presence of triethylamine. The cyano group in the resulting 5-cyano-1,2,4-triazines is readily replaced by reactions with various aliphatic alcohols and amines.

Angiotensin II receptor antagonistic 1,2,4-triazin-5-one derivatives

Disclosed are novel 1,2,4-triazin-5-one biphenyl derivatives having structural formula (I) useful as non-peptide antagonists of angiotensin II receptor: where R1 represents alkyl, cycloalkyl, or substituted or unsubstituted aryl; R2 represents alkyl, substituted or unsubstituted aryl, or arylalkyl; A and D independently represent C-R3, N, NH or C=O, wherein when A and D independently denote C-R3 or N, b and c are independently a double bond, and when A and D independently denote NH or C=O, b and c are independently a single bond; provided that b and c are not both double bonds; and R3 is hydrogen, dialkylphosphonate or halogen; and pharmaceutically acceptable salts thereof. Also disclosed is the use of the compounds of formula (I) as non-peptide antagonists of angiotensin II receptor, in the treatment of cardiovascular diseases, in particular hypertension and congestive heart failure.

STUDIES ON as-TRIAZINE DERIVATIVES. IV. SYNTHESIS OF UNSYMMETRICAL 5,6-DISUBSTITUTED 1,2,4-TRIAZINES

The reaction of 5-chloro-6-methyl-3-phenyl-1,2,4-triazine (4a) with ethylidenetriphenylphosphorane followed by the hydrolysis of the resulting as-triazinylphosphorane afforded 5-ethyl-6-methyl-3-phenyl-1,2,4-triazine (6a) in 88 percent yield.The condensat

Nouvelles voies d'acces aux diaryl-3,6 hydroxy-5 triazines-1,2,4 a partir des nitriles α-thioethers

Ar-C(CN)=N-N=C(CN)-Ar and Ar-C(CN)=N-NH-CO-Ar', easily prepared from the bromoderivates Ar-CBr(SEt)-CN, afford in good yields, by heating in a basic medium, 3,6-diaryl-5 hydroxy-1,2,4-triazines.