3752-97-4

Usage

Uses

Used in Organic Synthesis:
1,4-Bis(chloromethyl)-2,5-dimethoxybenzene is used as a building block for the synthesis of complex molecular structures due to its chloromethyl groups, which facilitate the formation of various chemical bonds and reactions.
Used in Research Applications:
This chemical is utilized in research settings for the study and development of new organic compounds and materials, given its unique structural properties and reactivity.
Used in Pharmaceutical Industry:
1,4-Bis(chloromethyl)-2,5-dimethoxybenzene may be employed as an intermediate in the synthesis of pharmaceutical compounds, leveraging its reactive sites for the creation of novel drug molecules.
Used in Chemical Industry:
In the chemical industry, 1,4-bis(chloromethyl)-2,5-dimethoxybenzene can be used as a precursor for the production of various specialty chemicals, taking advantage of its potential to form diverse chemical entities.

InChI:InChI=1/C10H12Cl2O2/c1-13-9-3-8(6-12)10(14-2)4-7(9)5-11/h3-4H,5-6H2,1-2H3

Upstream product

• 150-78-7 1,4-dimethoxybezene 
• 50-00-0 formaldehyd 
• 111-88-6 Octanethiol 
• 7647-01-0 hydrogenchloride 
• 123-91-1 1,4-dioxane 
• 51829-43-7 1,4-dihydroxymethyl-2,5-dimethoxybenzaldehyde 

Downstream Products

• 108651-24-7 1,4-dimethoxy-2,5-bis-thiocyanatomethyl-benzene 
• 38439-93-9 (2,5-dimethoxy-p-phenylene)-di-acetonitrile 
• 100964-58-7 2,5-bis(ethoxymethyl)-1,4-dimethoxybenzene 
• 7310-97-6 2,5-dimethoxyterephthalaldehyde 
• 124144-29-2 hexa-N-ethyl-N,N'-(2,5-dimethoxy-p-phenylenedimethyl)-di-ammonium; dichloride 
• 109451-94-7 hexa-N-methyl-N,N'-(2,5-dimethoxy-p-phenylenedimethyl)-di-ammonium; dichloride 
• 10273-64-0 1,4-bis(triphenylphosphoniomethyl)-2,5-dimethoxybenzene dichloride 
• 52251-27-1 1,4-bis(acetoxymethyl)-2,5-dimethoxybenzene 
• 2674-32-0 1,4-dimethoxy-2,5-dimethylbenzene 
• 5628-29-5 2,5-bis(chloromethyl)-1,4-benzoquinone 
• 120475-81-2 <4-(chloromethyl)-2,5-dimethoxybenzyl>triphenylphosphonium chloride 
• 13949-89-8 tetraethyl 1,4-diethyl-2,5-dimethoxybenzene-ω,ω,ω',ω'-tetracarboxylate 
• 4542-74-9 1,4-Dimethoxy-2,5-bis-iodmethyl-benzol 
• 5628-37-5 2,5-Bis(methoxymethyl)-1,4-dimethoxybenzene 

Relevant academic research and scientific papers

Structural and spectroscopic investigation on a new potentially bioactive di-hydrazone containing thiophene heterocyclic rings

Hydrazones and several substituted hydrazones are associated with a broad spectrum of biological activities, as well as compounds containing the thiophene ring. In this context, a novel di-hydrazone derived from 2-thiophenecarboxylic acid hydrazide was sy

Microcrystal induced emission enhancement of a small molecule probe and its use for highly efficient detection of 2,4,6-trinitrophenol in water

In this contribution, we reported a very simple and small molecule material, 2,5-dimethoxyterephthalaldehyde (DMA). It exhibited a relatively weak fluorescence in solution, while showed a steadily increased green fluorescence with typical aggregation- ind

Synthesis of novel tetra- and pentacyclic aza-cage systems

A novel route to substituted pentacyclic lactams and tetracyclic amides from bis(bromomethyl) and bis(chloromethyl) substituted pentacyclo[5.4.0.02,6.03,10.05,9]undeca-8, 11-diones is reported.

Synthesis of a novel chiral DA-TD covalent organic framework for open-tubular capillary electrochromatography enantioseparation

Herein, a novel chiral covalent organic framework, DA-TD COF, with good chemical/thermal stability was synthesized and used as a chiral stationary phase for open-tubular capillary electrochromatography enantioseparation. The DA-TD COF coated capillary exh

Real-time tracking of lipid droplets interactions with other organelles by a high signal/noise probe

Investigating the interactions between lipid droplets (LDs) and other organelles are greatly significant to the in-depth understand the physiology and pathology of LDs. Despite of commercial LDs probes available, the ER and other membrane structures are a

A novel bifunctional-group salamo-like multi-purpose dye probe based on ESIPT and RAHB effect: Distinction of cyanide and hydrazine through optical signal differential protocol

A novel bifunctional-group multi-purpose dye probe p-TNS has been designed and synthesized. The probe p-TNS has unique excited-state intramolecular proton transfer (ESIPT) and resonance-assisted hydrogen bonding (RAHB) coupled system, was confirmed to detect cyanide and hydrazine by blocking the ESIPT effect. Cyanide can change the fluorescence of the solution from bright green to orange-red (116 nm Stokes shift), while hydrazine causes the bright green fluorescence to be quenched. The recognition mechanism of the probe p-TNS to CN? and N2H4 was proposed reasonably through spectral characterizations and theoretical calculations. Combined with theoretical calculations, it was speculated that the solvent dependence may be caused by the ICT effect in the molecule. The probe p-TNS could be prepared into test strips for the detection of cyanide and hydrazine. In addition, the probe molecule can also be used to detect trace amounts of cyanide in agricultural products, and respond to gaseous hydrazine by direct contact, indicating that the probe p-TNS has good practical application prospects. Therefore, this molecular framework provides a new way of thinking about detecting multiple target substances.

Fluorescent dye for labeling virus, preparation method and application

The invention provides a fluorescent dye for marking viruses. Tetrazolyl is added on AIE fluorescent dye molecules. The fluorescent dye has high fluorescence labeling efficiency, is convenient for real-time tracking analysis of live viruses, and is suitab

Rational Fabrication of Crystalline Smart Materials for Rapid Detection and Efficient Removal of Ozone

Traditional ozone sensing and removal materials still suffer from high energy consumption and low efficiency. Thus, seeking new ozone-responsive materials with high efficiency and broad working conditions is of great significance. Herein, we first develop

Metalloporphyrin and Ionic Liquid-Functionalized Covalent Organic Frameworks for Catalytic CO2Cycloaddition via Visible-Light-Induced Photothermal Conversion

We report the construction of a porphyrin and imidazolium-ionic liquid (IL)-decorated and quinoline-linked covalent organic framework (COF, abbreviated as COF-P1-1) via a three-component one-pot Povarov reaction. After post-synthetic metallization of COF-P1-1 with Co(II) ions, the metallized COF-PI-2 is generated. COF-PI-2 is chemically stable and displays highly selective CO2 adsorption and good visible-light-induced photothermal conversion ability (ΔT = 26 °C). Furthermore, the coexistence of Co(II)-porphyrin and imidazolium-IL within COF-PI-2 has guaranteed its highly efficient activity for CO2 cycloaddition. Of note, the needed thermal energy for the reactions is derived from the photothermal conversion of the Co(II)-porphyrin COF upon visible-light irradiation. More importantly, the CO2 cycloaddition herein is a "window ledge"reaction, and it can proceed smoothly upon natural sunlight irradiation. In addition, a scaled-up CO2 cycloaddition can be readily achieved using a COF-PI-2@chitosan aerogel-based fixed-bed model reactor. Our research provides a new avenue for COF-based greenhouse gas disposal in an eco-friendly and energy- and source-saving way.

Interlayer Shifting in Two-Dimensional Covalent Organic Frameworks

Layer-stacking structures are very common in two-dimensional covalent organic frameworks (2D COFs). While their structures are normally determined under solvent-free conditions, the structures of solvated 2D COFs are largely unexplored. We report herein t