52251-27-1Relevant articles and documents
Condensation reactions of planar chiral tricarbonyl-chromium-complexed benzylic alcohols and acetates with reactive arenes
Rosca, Sorin I.,Stan, Raluca,Ott, Cristina,Parlea, Elena
, p. 327 - 333 (2011/04/27)
The condensation reaction of planar chiral 2- and 2,5-substituted tricarbonyl-chromium complexed benzylic alcohols and acetates with reactive arenes (durene, anisole, 1,3-dimethoxybenzene, diphenyl ether) is reported. The reactions were performed in both racemic and enantiomeric versions, optically pure and S-(-)-[2-methoxybenzyl alcohol]-tricarbonyl-chromium being prepared by LiAlH4 reduction of diastereomeric, t.l.c. separated, (-)-menthyl esters of [2-methoxybenzoic acis]-tricarbonyl-chromium. The condensation of the difunctional complex [1,4-diacetoxymethylene-2,5-dimethoxybenzene]-tricarbonyl- chromium with an excess of anisole proved the same reactivity at both reactive benzylic sites thus serving as a model for possible polycondensation process. Corresponding optically pure difunctional starting complexes were obtained by t.l.c. separation of diasteromeric diesters with R-(-)-lactic or S-(-)-mandelic acids.