52251-27-1

Upstream product

• 3752-97-4 1,4-bis(chloromethyl)-2,5-dimethoxybenzene 
• 127-09-3 sodium acetate 
• 50874-27-6 1,4-bis(bromomethyl)-2,5-dimethoxybenzene 
• 127-08-2 potassium acetate 
• 150-78-7 1,4-dimethoxybezene 
• 108-24-7 acetic anhydride 

Downstream Products

• 1951-36-6 2,5-dihydroxyterephthaldeyde 
• 668462-09-7 2-acetoxymethyl-5-hydroxymethyl-1,4-benzoquinone 
• 7310-97-6 2,5-dimethoxyterephthalaldehyde 
• 50874-27-6 1,4-bis(bromomethyl)-2,5-dimethoxybenzene 
• 87050-73-5 (E)-1,2-bis<4-<(acetyloxy)methyl>-2,5-dimethoxyphenyl>ethene 
• 120475-64-1 2,5-bisbromomethyl-1,4-benzoquinone 
• 120475-79-8 2,5-dimethoxy-4-(hydroxymethyl)benzaldehyde 
• 120475-80-1 4-(acetoxymethyl)-2,5-dimethoxybenzaldehyde 
• 120475-65-2 2,5-bis(hydroxymethyl)-1,4-benzoquinone bis(hydrogen succinate) 
• 120475-78-7 1,4-bis(hydroxymethyl)-2,5-dimethoxybenzene bis(hydrogen succinate) 
• 13949-78-5 2,5-bis(acetoxymethyl)-1,4-benzoquinone 
• 51829-43-7 1,4-dihydroxymethyl-2,5-dimethoxybenzaldehyde 

Relevant academic research and scientific papers

Condensation reactions of planar chiral tricarbonyl-chromium-complexed benzylic alcohols and acetates with reactive arenes

The condensation reaction of planar chiral 2- and 2,5-substituted tricarbonyl-chromium complexed benzylic alcohols and acetates with reactive arenes (durene, anisole, 1,3-dimethoxybenzene, diphenyl ether) is reported. The reactions were performed in both racemic and enantiomeric versions, optically pure and S-(-)-[2-methoxybenzyl alcohol]-tricarbonyl-chromium being prepared by LiAlH4 reduction of diastereomeric, t.l.c. separated, (-)-menthyl esters of [2-methoxybenzoic acis]-tricarbonyl-chromium. The condensation of the difunctional complex [1,4-diacetoxymethylene-2,5-dimethoxybenzene]-tricarbonyl- chromium with an excess of anisole proved the same reactivity at both reactive benzylic sites thus serving as a model for possible polycondensation process. Corresponding optically pure difunctional starting complexes were obtained by t.l.c. separation of diasteromeric diesters with R-(-)-lactic or S-(-)-mandelic acids.

Mono and bis(bioreductive) alkylating agents: Synthesis and antitumor activities in a B16 melanoma model

Several potentially bis(alkylating) bis(quinones) (3-5) and 1,4- and 1,3-bis(alkylating) monoquinones (6-13) belonging to general structure 2,2'-ethylenebis[5-[(leaving group) methyl]-1,4-benzoquinone] (3-5) and 2,5- and 2,6-bis[(leaving group)methyl]-1,4