37526-90-2Relevant academic research and scientific papers
9,10-SECOPREGNANE DERIVATIVE AND MEDICINE
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Paragraph 0146; 0147, (2016/11/28)
D3 vitamin a activity while having excellent the present invention refers to, systemic calcium metabolism on little effect of light guide plates, a polymer D3 vitamin a derivatives useful in. As the present invention, represented by formula 1 a 9, 10-seco
9,10-SECOPREGNANE DERIVATIVE AND PHARMACEUTICAL
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Page/Page column 10, (2009/03/07)
A main object of the invention is to provide a novel useful vitamin D3 derivative, which has an excellent vitamin D3 activity and, as compared with conventional vitamin D3 derivatives, has a relatively small amount of infl
9,10-SECOPREGNANE DERIVATIVE AND MEDICINE
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Page/Page column 14-15, (2008/06/13)
A novel useful vitamin D3 derivative which is reduced in influence on systemic calcium metabolism while retaining excellent vitamin D3 activity. The derivative is a 9,10-secopregnane derivative represented by the following general formula [1]. Also provided is a medicinal composition containing the derivative as an active ingredient. In the general formula [1], Y represents (1) a single bond, (2) alkylene, (3) alkenylene, or (4) phenylene; R1 and R2 are the same or different and each represents (1) hydrogen, (2) alkyl, or (3) cycloalkyl, or R1 and R2 in combination represent cycloalkyl in cooperation with the adjacent carbon atom; R3 represents hydrogen or methyl; and Z represents (1) hydrogen, (2) hydroxy, or (3) -NR11R12.
A New and Facile Method for the Direct Preparation of α-Hydroxycarboxylic Acid Esters from α,β-Unsaturated Carboxylic Acid Esters with Molecular Oxygen and Phenylsilane Catalyzed by Bis(dipivaloylmethanato)manganese(II) Complex
Inoki, Satoshi,Kato, Koji,Isayama, Shigeru,Mukaiyama, Teruaki
, p. 1869 - 1872 (2007/10/02)
In the presence of a catalytic amount of bis(dipivaloylmethanato)manganese(II) complex, the oxygenation of benzyl crotonate with molecular oxygen and phenylsilane proceeds smoothly under a mild condition to give benzyl 2-hydroxybutyrate in high yield.The reaction provides a new and convenient method for the direct preparation of various α-hydroxycarboxylic acid esters starting from α,β-unsaturated carboxylic acid esters.The influence of substituents of olefins on regioselectivity is also studied.
