3753-05-7

Basic information

• Product Name: ETHYLENE GLYCOL BIS(4-CARBOXYPHENYL) ETHER
• Synonyms: 4,4’-[1,2-ethanediylbis(oxy)]bis(benzoicacid);4,4’-[1,2-ethanediylbis(oxy)]bis-benzoicaci;benzoicacid,4,4’-[1,2-ethanediylbis(oxy)]bis-;ethyleneglycolbiscarboxyphenylether;ETHYLENE GLYCOL BIS(4-CARBOXYPHENYL) ETHER;ETHYLENE GLYCOL BIS(P-CARBOXYPHENYL) ETHER;1,2-BIS(4-CARBOXYPHENOXY)ETHANE;4,4-ethanediyldioxydibenzoic acid
• CAS NO: 3753-05-7
• Molecular Formula: C₁₆H₁₄O₆
• Molecular Weight: 302.28
• EINECS: 223-155-8
• Product Categories: Fluorenes, etc. (reagent for high-performance polymer research);Functional Materials;Reagent for High-Performance Polymer Research
• Mol File: 3753-05-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 352-355 °C
• Boiling Point: 546.2°Cat760mmHg
• Flash Point: 205.3°C
• Appearance: /
• Density: 1.353g/cm³
• Vapor Pressure: 9.16E-13mmHg at 25°C
• Refractive Index: 1.612
• PKA: 4.10±0.10(Predicted)
• CAS DataBase Reference: ETHYLENE GLYCOL BIS(4-CARBOXYPHENYL) ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYLENE GLYCOL BIS(4-CARBOXYPHENYL) ETHER(3753-05-7)
• EPA Substance Registry System: ETHYLENE GLYCOL BIS(4-CARBOXYPHENYL) ETHER(3753-05-7)

Safety Data

• Hazardous Substances Data: 3753-05-7(Hazardous Substances Data)

Usage

General Description

Ethylene glycol bis(4-carboxyphenyl) ether is a chemical compound with the formula C14H12O6. It is commonly used as a crosslinking agent in the production of epoxy resins, which are important in the construction and automotive industries. It is also utilized as a building block for the synthesis of various polymers and materials. Additionally, ethylene glycol bis(4-carboxyphenyl) ether has potential applications in the electronics and telecommunications industries due to its high thermal stability and electrical properties. However, it is important to handle this compound with care as it can be harmful if ingested or inhaled and may cause skin irritation upon contact.

InChI:InChI=1/C16H14O6/c17-15(18)11-1-5-13(6-2-11)21-9-10-22-14-7-3-12(4-8-14)16(19)20/h1-8H,9-10H2,(H,17,18)(H,19,20)

Upstream product

• 34074-28-7 1,2-bis(4-formylphenoxy)ethane 
• 15149-11-8 1,1'-[ethane-1,2-diylbis(oxy)]bis(4-methylbenzene) 
• 107-06-2 1,2-dichloro-ethane 
• 99-96-7 4-hydroxy-benzoic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 106-93-4 ethylene dibromide 

Downstream Products

• 10604-81-6 1,2-bis(4'-carboxy-phenoxy)ethane diacid dichloride 
• 1430742-33-8 {[Zn(bce)(H₂O)]}n 

Relevant articles and documents

Encapsulation and sensitization of UV-vis and near infrared lanthanide hydrate emitters for dual- and bimodal-emissions in both air and aqueous media based on a porous heteroatom-rich Cd(II)-framework

A porous heteroatom-rich Cd(II)-polymeric framework which is generated from an ethylene glycol ether-bridging dicarboxylate ligand L, 4,4′-bipy and Cd(II) ion is reported. It contains one-dimensional tubes (9-11 ?) which are able to trap cationic lanthanide hydrates such as Eu(H2O) 83+, Tb(H2O)83+, and Nd(H2O)83+ under ambient conditions to generate Ln(H2O)83+-loaded materials. In addition, the heteroatom-rich host material can effectively protect and sensitize the encapsulated Ln3+ emitters in their hydrate form in both air and aqueous media. Furthermore, the dual- and bimodal-emissions are successfully realized by intercalation of the different Ln3+-hydrates based on a guest-driven approach.

Biological evaluation of bisbenzaldehydes against four Mycobacterium species

A series of bisbenzaldehydes and structurally related analogs, conveniently synthesized via microwave-assisted reactions, were evaluated in vitro against drug susceptible and multi-drug resistant Mycobacterium tuberculosis, against virulent Mycobacterium bovis, against Mycobacterium ulcerans and against two Mycobacterium avium subspecies. Among the 33 substances that were tested, compound 12, i.e. 4,4′-[1,12-dodecanediyl(oxy)]bisbenzaldehyde, emerged as the most promising hit. Its activity was further confirmed in an intracellular growth inhibition assay of M. tb in murine J774 A.1 macrophages. None of the compounds showed significant cytotoxicity on human C3A hepatocytes in a neutral red dye uptake assay and no genotoxicity or mutagenicity was observed as demonstrated by a VITOTOX test and confirmed with a comet assay.

Process for preparing α,ω-bis(2-chlorophenoxy)alkane-4,4'-dicarboxylic acid or its lower alkyl ester

A process for producing an α,ω-bis(2-chlorophenoxy)alkane-4,4'-dicarboxylic acid or its ester, that has a high Young's modulus and that is useful as a material for polyesters capable to form self-extinguishing fibers and films. Thus α,ω-bis(2-chlorophenoxy)alkane-4,4'-dicarboxylic acid or its ester is obtained by reacting α,ω-bis(phenoxy)alkane-4,4'-dicarboxylic acid or its ester with chlorine in the presence of a solvent selected from the group consisting of lower fatty acid having 2 to 6 carbon atoms, hydrocarbon chloride having 1 to 8 carbon atoms, and carbon chloride having 1 to 2 carbon atoms, in high yield.