37553-95-0Relevant academic research and scientific papers
A urethane-based paint film composition
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, (2007/10/09)
PROBLEM TO BE SOLVED: To provide a urethane-base coating-film waterproof material composition odorless and excellent in mixability, curability and finishing touches, low in viscosity and hard to foam. SOLUTION: This urethane-base coating-film waterproof material composition comprises a urethane prepolymer, a curing agent, and 2,2,4-trimethyl-1,3-pentane diol diisobutyrate, wherein the 2,2,4-trimethyl-1,3-pentane diol diisobutyrate is contained in an amount of 1-15 pts. by mass to 100 pts. by mass of components other than the 2,2,4-trimethyl-1,3-pentane diol diisobutyrate. COPYRIGHT: (C)2006,JPOandNCIPI
A regiospecific synthesis of protoberberine alkaloids
Kiparissides, Zinovia,Fichtner, Robert H.,Poplawski, Janusz,Nalliah, Bala C.,MacLean, David B.
, p. 2770 - 2779 (2007/10/02)
The protoberberine skeleton has been prepared in two steps from N-benzyl-3,4-dihydroisoquinolinium salts.Treatment of the salts with the anion of methyl methylthiomethylsulfoxide yields mixtures of diastereomeric adducts that cyclize on heating with concentrated hydrochloric acid to dihydroprotoberberines.The latter compounds may be reduced to their tetrahydro analogues with sodium borohydride, oxidized to protoberberinium salts with iodine, or converted to 13-methyltetrahydroprotoberberines by treatment with formaldehyde according to an established procedure.The method has been applied successfully to the synthesis of (+/-)-tetrahydropalmatine, palmatine iodide, (+/-)-xylopinine, (+/-)-sinactine, and (+/-)-corydaline.N-Benzylisoquinolinium salts may be used in place of their dihydro analogues as starting materials in this synthesis, thereby extending the range of substitution patterns potentially available.
