375819-13-9Relevant academic research and scientific papers
Direct organocatalytic enantioselective α-aminomethylation of ketones
Ibrahem, Ismail,Zou, Weibiao,Casas, Jesús,Sundén, Henrik,Córdova, Armando
, p. 357 - 364 (2007/10/03)
The scope and limitations of the direct organocatalytic asymmetric α-aminomethylation of ketones are disclosed. The proline-catalyzed classical Mannich reactions between unmodified ketones, aqueous formaldehyde and aromatic amines furnished the desired Ma
Enzyme-catalysed kinetic resolution of N,O-diacetyl derivatives of cyclic 1,3-amino alcohols
Kaman, Judit,Forro, Eniko,Fueloep, Ferenc
, p. 1881 - 1886 (2007/10/03)
Racemates of N,O-diacetyl derivatives of cis- and trans-2-aminomethylcyclopentanols 5 and 6 and cis- and trans-2-aminomethylcyclohexanols 7 and 8 were resolved through lipase-catalysed asymmetric O-deacylation at the (1R) stereogenic centre. The gram-scal
