840475-22-1Relevant academic research and scientific papers
Direct organocatalytic enantioselective α-aminomethylation of ketones
Ibrahem, Ismail,Zou, Weibiao,Casas, Jesús,Sundén, Henrik,Córdova, Armando
, p. 357 - 364 (2006)
The scope and limitations of the direct organocatalytic asymmetric α-aminomethylation of ketones are disclosed. The proline-catalyzed classical Mannich reactions between unmodified ketones, aqueous formaldehyde and aromatic amines furnished the desired Ma
