37619-50-4

Usage

Uses

Used in Organic Synthesis:
(6-methyl-1,4-dioxaspiro[4.4]non-6-yl)methanol is used as a key intermediate in the synthesis of various organic compounds due to its unique spiro ring structure, which can be manipulated to create a wide range of molecules with different functionalities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (6-methyl-1,4-dioxaspiro[4.4]non-6-yl)methanol is used as a building block for the development of new drugs and biologically active molecules. Its specific properties allow for the creation of novel therapeutic agents that can potentially target a variety of medical conditions.
Used in Research and Development:
(6-methyl-1,4-dioxaspiro[4.4]non-6-yl)methanol is also utilized in research and development settings as a subject of study for further understanding its chemical behavior, reactivity, and potential applications in various fields, including material science and chemical engineering.

Upstream product

• 151700-09-3 C₁₀H₁₆O₄ 
• 30680-84-3 methyl 1-methyl-2-oxocyclopentane-1-carboxylate 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 5453-88-3 ethyl 1-methyl-2-oxocyclopentane-1-carboxylate 
• 107-21-1 ethylene glycol 

Downstream Products

• 37619-38-8 2-methyl-2-<<<(4-methylphenyl)sulfonyl>oxy>methyl>cyclopentanone 
• 118975-57-8 2-(iodomethyl)-2-methylcyclopentanone O-(phenylmethyl)oxime 
• 4541-32-6 2,2-dimethylcyclopentanone 

Relevant academic research and scientific papers

Preparation method of 2, 2-dimethyl cyclopentanone

The invention discloses a preparation method of 2, 2-dimethyl cyclopentanone, which comprises the following steps: methylating 2-methoxycarbonyl cyclopentanone to obtain a methylated product 2-methyl-2-methoxycarbonyl cyclopentanone, carrying out keto-carbonyl protection on the methylated product to obtain a protected product 2-methyl-2-methoxycarbonyl cyclopentanone ketal, carrying out ester group reduction on the protection product to obtain an alcohol product 2-hydroxymethyl-2-methyl cyclopentanone ketal, carrying out deprotection on the alcohol product under an acidic condition to obtain a deprotection product 2-hydroxymethyl-2-methyl cyclopentanone, and brominating the deprotection product to obtain 2-bromomethyl-2-methyl cyclopentanone. All raw materials adopted by the method are low in cost and easy to obtain in the market, and reactions in all steps are conventional reactions and easy to implement; the process is simple, mild in reaction condition and easy to operate; the reaction time is short, control is easy, the yield of each step is 90% or above, and industrial large-scale production is easy to achieve.

Oxidation of 1-hydroxyazetidines to four-membered cyclic nitrones and β-lactams

The 1-(benzyloxy)azetidines 7a-c and 16a,b were synthesized by reductive cyclization of the corresponding oximes 5a-c and 14a-d.Oxidation of the 1-hydroxyazetidines 8a-c and 17 with PbO2 afforded the corresponding four-membered cyclic nitrones 18a-c and t